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Cat. No.: HY-106305

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Ledoxantrone

Name: Ledoxantrone
Brand: MedChemExpress
SKU: HY-106305
Availability: PreOrder

(Synonyms: CI 958)

Ledoxantrone (CI 958) is a DNA helicases inhibitor with an IC₅₀ of 0.17 μM. Ledoxantrone can be used in the study of prostate cancer.

For research use only. We do not sell to patients.

CAS No.: 113457-05-9
Formula: C₂₁H₂₇N₅OS
Molecular Weight:397.54

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Ledoxantrone Chemical Structure

CAS No.: 113457-05-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Ledoxantrone (CI 958) is a DNA helicases inhibitor with an IC₅₀ of 0.17 μM. Ledoxantrone can be used in the study of prostate cancer^[1].

IC₅₀ & Target

Helicase

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 113457-05-9
Molecular Weight 397.54
Formula C₂₁H₂₇N₅OS
SMILES

OC1=CC(SC2=C(NCCN)C=CC3=C2C4=NN3CCN(CC)CC)=C4C=C1
Synonyms

CI 958
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lun L, et al. Antihelicase action of CI-958, a new drug for prostate cancer. Cancer Chemother Pharmacol. 1998;42(6):447-53. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Protocols
Purity & Documentation
References

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Ledoxantrone

All DNA/RNA Synthesis Isoforms

Biological Activity

Description

IC50 & Target

Chemical Information

Protocols

Purity & Documentation

References

Calculators

Help & FAQs

Ledoxantrone Related Classifications

HY-106305 Related Classifications

Bioz

Keywords

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