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Cat. No.: HY-N18297

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Licoagrochalcone A

Licoagrochalcone A is a PTP1B inhibitor. Licoagrochalcone A exerts protective effects against liver cell injury induced by carbon tetrachloride and Acetaminophen (HY-66005). Licoagrochalcone A is applicable to the research of type 2 diabetes, obesity and liver injury.

For research use only. We do not sell to patients.

CAS No.: 202815-28-9
Formula: C₂₀H₂₀O₄
Molecular Weight:324.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Licoagrochalcone A Chemical Structure

CAS No.: 202815-28-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HEK-293T	GI	2 % Compound: 4	Growth inhibition of human HEK293T cells at 10 uM after 24 hrs by MTS assay relative to control Growth inhibition of human HEK293T cells at 10 uM after 24 hrs by MTS assay relative to control	[PMID: 28522265]

In Vitro

Licoagrochalcone A exerts significant potent hepatoprotective effects against CCl₄- and Acetaminophen (HY-66005)-induced injury in HepG2 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 202815-28-9
Molecular Weight 324.37
Formula C₂₀H₂₀O₄
SMILES

C/C(C)=C\CC1=CC(/C=C/C(C2=C(C=C(C=C2)O)O)=O)=CC=C1O
Structure Classification
- Flavonoids
- Chalcones
- Phenols
- Polyphenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wang D, et al. Natural Chalcones in Chinese Materia Medica: Licorice. Evid Based Complement Alternat Med. 2020 Mar 16;2020:3821248. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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