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Cat. No.: HY-W150222

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LIMK1-IN-3

LIMK1-IN-3 is a LIMK1 inhibitor with an IC₅₀ of 4.4 μM. LIMK1-IN-3 shows potential for use in cancer-related research.

For research use only. We do not sell to patients.

CAS No.: 4994-89-2
Formula: C₈H₉N₃S
Molecular Weight:179.24

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

LIMK1-IN-3 Chemical Structure

CAS No.: 4994-89-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

LIMK1-IN-3 is a LIMK1 inhibitor with an IC₅₀ of 4.4 μM. LIMK1-IN-3 shows potential for use in cancer-related research^[1].

IC₅₀ & Target^[1]

LIMK1

4.4 μM (IC₅₀)

All LIM Kinase (LIMK) Isoforms :

LIMK1
LIMK2

In Vitro

LIMK1-IN-3 (compound 12) inhibits purified LIMK1 kinase with an IC₅₀ of 4.4 μM in cell-free KinaseGlo and TR-FRET assays^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 4994-89-2
Molecular Weight 179.24
Formula C₈H₉N₃S
SMILES

N=1C=NC(N)=C2C1SC(=C2C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Sleebs BE, et al. Identification of 5,6-substituted 4-aminothieno[2,3-d]pyrimidines as LIMK1 inhibitors. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5992-4. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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