Polyketides

Helicianeoide A is a Flavonoids product that can be isolated from the roots of Helicia erratica Hook. f..

Gelomuloside A is a Flavonoids product that can be isolated from the leaves of Suregada multiflora..

Anhydrotuberosin is a Flavonoids product that can be isolated from the roots of Pueraria lobata.

7,3'-Dihydroxy-4'-methoxyflavan is a Flavonoids product that can be isolated from the branches of Broussonetia papyrifera.

Isorhamnetin-3-O-sophoroside-7-O-rhamnoside, the major flavonol glycoside, is isolated from sea buckthorn (Hippopha rhamnoides). Isorhamnetin-3-O-sophoroside-7-O-rhamnoside has the algicidal activity against the growth of the harmful microalgae.

Vitexin2''-O-p-coumarate is isolated from fenugreek seeds. Vitexin2''-O-p-coumarate strongly promotes 2BS cell proliferation induced by H₂O₂.

4'-O-Methylpreglabridin is a prenylated isoflavone precursor of Glabridin (HY-N0393), and it can be converted into Glabridin via one-step oxidative cyclization catalyzed by GgOC family enzymes.

Tamarixetin-3-O-rutinoside is a flavonol glycoside identified from quinoa grains and white rapeseed petals. Tamarixetin-3-O-rutinoside shows a significant negative correlation with betacyanin content. The content of Tamarixetin-3-O-rutinoside is down-regulated in leaves and roots of transgenic tobacco plants overexpressing GbDFR6, and it can serve as a candidate regulator of auxin transport. Tamarixetin-3-O-rutinoside can be used in studies related to the regulation of plant pigment metabolism.

Ageconyflavone C is a natural pentamethoxyflavonoid found in the aerial parts of Ageratum conyzoides L. Ageconyflavone C inhibits Trypanosoma brucei rhodesiense, Leishmania donovani, and Chloroquine (HY-17589A)- and Pyrimethamine (HY-18062)-resistant Plasmodium falciparum K1, with IC₅₀ values of 7.8, 9.2, and 9.25 μM, respectively. Ageconyflavone C can be used in studies related to anti-protozoal and parasitic infection research.

Licocoumarone is an active component derived from licorice. Licocoumarone has an IC₅₀ of 12.56 μM and a K_d of 14.90 μM against human DYRK1A. Licocoumarone inhibits NF-κB activation by blocking IκBα degradation and p65 phosphorylation, interferes with MAPK activation via inhibiting phosphorylation, and downregulates the expression of iNOS. Licocoumarone inhibits LPS-induced expression of IL-1β, IL-6 and IL-10; it induces apoptosis of pancreatic cancer cells apoptosis and acts as a neuraminidase inhibitor (IC₅₀ = 27.8 μM). Licocoumarone exhibits anti-inflammatory and antimicrobial activities, with antibacterial activity against Listeria and antifungal activity against Candida parapsilosis. Licocoumarone can be used in studies related to immune and inflammatory diseases, pancreatic cancer, and specific bacterial and fungal infections.

Rhamnetin 3-O-rutinoside is an antihyperglycemic agent. Rhamnetin 3-O-rutinoside reduces blood glucose levels. Rhamnetin 3-O-rutinoside decreases serum levels of total cholesterol, triglycerides, urea, creatinine, aspartate aminotransferase (SGOT) and alanine aminotransferase (SGPT). Rhamnetin 3-O-rutinoside can be used in studies related to diabetes.

Neomethymycin (Compound5) is a 12-membered ring macrolide natural product. Neomethymycin can be found in engineered Streptomyces venezuelae ATCC 15439 strain DHS2001, where it forms via biotransformation of 10-deoxymethyonolide.

4-O-Methylhelichrysetin is a Chalcones product that can be isolated from the herbs of Cephalotaxus sinensis.

(E/Z)-6'-Hydroxy-3,4,2',3',4'-pentamethoxychalcone (Compound 5) is a chalcone found in Chromolaena odorata (L.) King & Robinson.

Hibiscetin heptamethyl ether is a natural product isolated from various medicinal plants.

3',4',5',3,5,6,7-Heptamethoxyflavone (NSC 684433) is a product that can be isolated from .

4,4'-Dihydroxy-2',6'-dimethoxychalcone is a Chalcones product that can be isolated from the herbs of Alpinia galanga.

2',4'-Dihydroxy-2,3',6'-trimethoxychalcone, a flavonoid, is a natural product that can be isolated from the roots of Scutellaria Luzonicatropical.

Kanjone is a compound found in Millettia peguensis and can be used for the synthesis of protein tyrosine phosphatase 1B (PTP1B) inhibitors. Kanjone holds promise for research in the fields of diabetes and neurological disorders.

Broussoflavonol G is an active ingredient of Moraceae plants, which can be isolated from Broussonetia papyrifera. Broussoflavonol G can effectively inhibit Fe²⁺-induced lipid oxidation in rat brain homogenate and significantly inhibit the proliferation of rat vascular smooth muscle cells.