2. Epigenetics Immunology/Inflammation
  3. PD-1/PD-L1 Histone Demethylase
  4. LSD1-IN-27

LSD1-IN-27 (Compound 5ac) is a LSD1 inhibitor (IC50: 13 nM). LSD1-IN-27 inhibits the stemness and migration of gastric cancer cells. LSD1-IN-27 also reduces the expression of PD-L1 in BGC-823 and MFC cells. LSD1-IN-27 can enhance T cell immune response in gastric cancer.

For research use only. We do not sell to patients.

LSD1-IN-27 Chemical Structure

LSD1-IN-27 Chemical Structure

CAS No. : 2904571-94-2

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LSD1-IN-27 Related Antibodies

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Description

LSD1-IN-27 (Compound 5ac) is a LSD1 inhibitor (IC50: 13 nM). LSD1-IN-27 inhibits the stemness and migration of gastric cancer cells. LSD1-IN-27 also reduces the expression of PD-L1 in BGC-823 and MFC cells. LSD1-IN-27 can enhance T cell immune response in gastric cancer[1].

IC50 & Target

13 nM (LSD1)[1]
Molecular Weight

355.48

Formula

C24H25N3
CAS No.
SMILES

CC1=CC=C2C(C(NC3=CC=C(N(C)C)C=C3)=C4C(C(C)=C(C)C=C4)=N2)=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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LSD1-IN-27 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LSD1-IN-272904571-94-2PD-1/PD-L1Histone DemethylasePD-1/Programmed death-ligand 1T cellimmuneMFC cellgastric cancerBGC-823Inhibitorinhibitorinhibit

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