1. MAPK/ERK Pathway
  2. p38 MAPK
  3. MBP MAPK Substrate

MBP MAPK Substrate is used as an exogenous substrate for MAPK.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

MBP MAPK Substrate

MBP MAPK Substrate Chemical Structure

CAS No. : 138028-00-9

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Description

MBP MAPK Substrate is used as an exogenous substrate for MAPK[1].

Molecular Weight

967.09

Formula

C39H70N18O11

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Ala-Pro-Arg-Thr-Pro-Gly-Gly-Arg-Arg

Sequence Shortening

APRTPGGRR

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (103.40 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0340 mL 5.1701 mL 10.3403 mL
5 mM 0.2068 mL 1.0340 mL 2.0681 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.58%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.0340 mL 5.1701 mL 10.3403 mL 25.8507 mL
5 mM 0.2068 mL 1.0340 mL 2.0681 mL 5.1701 mL
10 mM 0.1034 mL 0.5170 mL 1.0340 mL 2.5851 mL
15 mM 0.0689 mL 0.3447 mL 0.6894 mL 1.7234 mL
20 mM 0.0517 mL 0.2585 mL 0.5170 mL 1.2925 mL
25 mM 0.0414 mL 0.2068 mL 0.4136 mL 1.0340 mL
30 mM 0.0345 mL 0.1723 mL 0.3447 mL 0.8617 mL
40 mM 0.0259 mL 0.1293 mL 0.2585 mL 0.6463 mL
50 mM 0.0207 mL 0.1034 mL 0.2068 mL 0.5170 mL
60 mM 0.0172 mL 0.0862 mL 0.1723 mL 0.4308 mL
80 mM 0.0129 mL 0.0646 mL 0.1293 mL 0.3231 mL
100 mM 0.0103 mL 0.0517 mL 0.1034 mL 0.2585 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
MBP MAPK Substrate
Cat. No.:
HY-P2456
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