1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. MC-Val-Ala-PBD

MC-Val-Ala-PBD 

Cat. No.: HY-101162
Handling Instructions

MC-Val-Ala-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, pyrrolobenzodiazepine (PBD, a cytotoxic DNA crosslinking), linked via the cleavable linker MC-Val-Ala.

For research use only. We do not sell to patients.

MC-Val-Ala-PBD Chemical Structure

MC-Val-Ala-PBD Chemical Structure

CAS No. : 1342820-51-2

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Description

MC-Val-Ala-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, pyrrolobenzodiazepine (PBD, a cytotoxic DNA crosslinking), linked via the cleavable linker MC-Val-Ala[1].

IC50 & Target[1]

Pyrrolobenzodiazepines

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Molecular Weight

1089.20

Formula

C₆₀H₆₄N₈O₁₂

CAS No.

1342820-51-2

SMILES

O=C(C1=CC(OC)=C(OCCCOC(C=C(N=C[[email protected]@]2([H])N(C=C(C3=CC=C(OC)C=C3)C2)C4=O)C4=C5)=C5OC)C=C1N=C6)N7[[email protected]@]6([H])CC(C8=CC=C(NC([[email protected]](C)NC([[email protected]](C(C)C)NC(CCCCCN(C9=O)C(C=C9)=O)=O)=O)=O)C=C8)=C7

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

MC-Val-Ala-PBDDrug-Linker Conjugates for ADCPyrrolobenzodiazepineDNAcrosslinkingantitumorADCcleavableInhibitorinhibitorinhibit

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MC-Val-Ala-PBD
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