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Cat. No.: HY-179908

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MEK-IN-8

MEK-IN-8 (Compound 30) is a MEK inhibitor (IC₅₀: < 5 nM for pMEK in A549 cells). MEK-IN-8 can be used in tumor research.

For research use only. We do not sell to patients.

CAS No.: 3002056-26-7
Formula: C₂₄H₂₁F₂N₃O₆S
Molecular Weight:517.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

MEK-IN-8 Chemical Structure

CAS No.: 3002056-26-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

MEK-IN-8 (Compound 30) is a MEK inhibitor (IC₅₀: < 5 nM for pMEK in A549 cells). MEK-IN-8 can be used in tumor research^[1].

All MEK Isoforms :

Chemical Information

CAS No. 3002056-26-7
Molecular Weight 517.50
Formula C₂₄H₂₁F₂N₃O₆S
SMILES

O=C1OC2=C(C(C)=C1CC3=C(F)C(NS(=O)(NCCO)=O)=CC=C3)C=CC(OC4=NC=CC=C4F)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Margit Hagel, et al. Heterocyclic derivative as mitogen-activated protein kinase (mek) inhibitor. WO2024226579A1. WIPO (PCT). 2023-04-24.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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MEK-IN-8

All MEK Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

MEK-IN-8 Related Classifications

HY-179908 Related Classifications