MG 149 (Standard)
MG 149 (Standard) is the analytical standard of MG 149 (HY-15887). This product is intended for research and analytical applications. MG149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF (IC50 = 47 uM); little potent for PCAF and p300 (IC50 >200 uM). MG 149 inhibits KAT8 and blocks PINK1 Kinase activity. MG149 inhibits the phosphorylation of ParKin and ubiquitin, thereby suppressing the initiation of PINK1-dependent mitophagy. MG 149 can reverse chronic restraint stress (CRS) induced hypertension and related molecular changes. MG 149 commonly used in research on diseases such as hypertension and ParKinson's disease.
For research use only. We do not sell to patients.
- CAS No.: 1243583-85-8
- Formula: C22H28O3
- Molecular Weight:340.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1243583-85-8
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Molecular Weight 340.46
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Formula C22H28O3
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SMILES
O=C(O)C1=C(O)C=CC=C1CCC2=CC=C(CCCCCCC)C=C2
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Synonyms
Tip60 HAT inhibitor (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MG 149 (Standard) Related Classifications
HY-15887R Related Classifications
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