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Cat. No.: HY-153001

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MK-8389

MK-8389 is an orally active LMW allosteric FSH receptor agonist. MK-8389 affects thyroid function.

For research use only. We do not sell to patients.

CAS No.: 1177015-12-1
Formula: C₂₇H₃₄N₂O₂S
Molecular Weight:450.64

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

MK-8389 Chemical Structure

CAS No.: 1177015-12-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

MK-8389 is an orally active LMW allosteric FSH receptor agonist. MK-8389 affects thyroid function^[1].

All Estrogen Receptor/ERR Isoforms :

Chemical Information

CAS No. 1177015-12-1
Molecular Weight 450.64
Formula C₂₇H₃₄N₂O₂S
SMILES

O=C(N(C(C)(C)C)C)C1=CC(C2=CC=CS2)=C3C4=C(CCN13)C=C(OC)C(CC(C)C)=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gerrits MG, et al. Oral follicle-stimulating hormone agonist tested in healthy young women of reproductive age failed to demonstrate effect on follicular development but affected thyroid function. Fertil Steril. 2016 Apr;105(4):1056-1062.e4. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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MK-8389

All Estrogen Receptor/ERR Isoforms