MMA-NODAGA
MMA-NODAGA is a chelator for site-specific labeling of targeting proteins containing unpaired cysteine. MMA-NODAGA can be used to conjugate with exosome and 64Cu in image with positron emission tomography (PET).
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- CAS No.: 1440903-11-6
- Formule: C21H31N5O9
- Masse moléculaire:497.50
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Stockage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Activité biologique
Description
IC50 & Target
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RDC Bifunctional Chelator |
Chemical Information
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CAS No. 1440903-11-6
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Appearance Solid
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Masse moléculaire 497.50
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Formule C21H31N5O9
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Color White to off-white
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SMILES
O=C(CN1CCN(CCN(C(CCC(NCCN2C(C=CC2=O)=O)=O)C(O)=O)CC1)CC(O)=O)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Pureté et documentation
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Fiche technique (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Sara F F Almeida , et al. Osteosarcoma-Derived Exosomes as Potential PET Imaging Nanocarriers for Lung Metastasis. Small. 2022 Dec;18(49):e2203999. [Content Brief]
[2]. Mohamed Altai, et al. Influence of nuclides and chelators on imaging using affibody molecules: comparative evaluation of recombinant affibody molecules site-specifically labeled with ⁶⁸Ga and ¹¹¹In via maleimido derivatives of DOTA and NODAGA. Bioconjug Chem. 2013 Jun 19;24(6):1102-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)