Monogynol A

Cat. No.: HY-N19871: Data Sheet Handling Instructions
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Monogynol A is an AChE/BChE inhibitor found in the aerial parts of Salvia trichoclada Bentham. Monogynol A can be used for the research of alzheimer’s disease.

For research use only. We do not sell to patients.

Monogynol A Chemical Structure

CAS No. : 7788-20-7

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AChE BChE

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References
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Description

Monogynol A is an AChE/BChE inhibitor found in the aerial parts of Salvia trichoclada Bentham. Monogynol A can be used for the research of alzheimer’s disease^[1].

IC₅₀ & Target^[1]

AChE

BChE

In Vitro

Monogynol A (Compound 4) (10-100 μM; 30 min) does not exhibit DPPH free radical scavenging activity^[1].
Monogynol A (10-100 μM; 2 h at 50 °C) does not exhibit lipid peroxidation inhibitory activity in the β-carotene (HY-N0411) bleaching assay^[1].
Monogynol A (25-200 μM; 15 min at 25 °C) exhibits moderate dose-dependent AChE inhibitory activity^[1].
Monogynol A (25-200 μM; 15 min at 25 °C) exhibits moderate dose-dependent BChE inhibitory activity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

444.73

Formula

C₃₀H₅₂O₂

CAS No.

7788-20-7

SMILES

C[C@]12[C@]3([C@@](CC[C@]1([H])[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC2)C)([H])[C@]5([H])[C@@](CC3)(CC[C@H]5C(C)(O)C)C)C

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Çulhaoğlu B, et al. Antioxidant and anticholinesterase activities of lupane triterpenoids and other constituents of Salvia trichoclada. Med. Chem. Res. 2015 Aug 20;24:3831–3837.

Monogynol A Related Classifications

Neurological Disease

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Monogynol A7788-20-7Cholinesterase (ChE)butyrylcholinesteraseacetylcholinesteraseβ-carotene-linoleic acid systemlipid peroxidationalzheimer’s diseaseDPPH free radicalβ-carotene bleaching assayInhibitorinhibitorinhibit

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