Mrgx2 antagonist-2
Mrgx2 antagonist-2 (Example 132) is a Mrgx2 antagonist with a pIC50 of 8.6. Mrgx2 antagonist-2 can be used in the research of MrgX2 -mediated diseases or disorders.
For research use only. We do not sell to patients.
- CAS No.: 2767111-67-9
- Formula: C23H21F4N5O3
- Molecular Weight:491.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Mrgx2[1]
MrgX2 can mediate a variety of diseases, including chronic spontaneous urticaria, mast cell hyperplasia, cold-induced urticaria, atopic dermatitis, rosacea, Crohn's disease, ulcerative colitis, irritable bowel syndrome, rheumatoid arthritis, fibromyalgia, nasal polyps, neuropathic pain, inflammatory pain, chronic pruritus, drug-induced allergic-like reactions, metabolic syndrome, esophageal reflux, asthma, cough, migraine, chronic provoked urticaria, chronic pruritus syndrome, acute pruritus, nodular pruritus, osteoarthritis, pseudo-allergic reaction or contact urticaria, etc[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2767111-67-9
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Molecular Weight 491.44
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Formula C23H21F4N5O3
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SMILES
FC1([C@@H](C2=CC=[N+]([O-])C=C2)CN(CC1)[C@@H](C)C(NC3=NC=C(OC4=C(C=C(C=C4)F)F)N=C3)=O)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)