Mrgx2 antagonist-2
Mrgx2 antagonist-2 (Example 132) is a Mrgx2 antagonist with a pIC50 of 8.6. Mrgx2 antagonist-2 can be used in the research of MrgX2 -mediated diseases or disorders.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2767111-67-9
- 分子式: C23H21F4N5O3
- 分子量:491.44
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
Mrgx2[1]
体外実験
MrgX2 can mediate a variety of diseases, including chronic spontaneous urticaria, mast cell hyperplasia, cold-induced urticaria, atopic dermatitis, rosacea, Crohn's disease, ulcerative colitis, irritable bowel syndrome, rheumatoid arthritis, fibromyalgia, nasal polyps, neuropathic pain, inflammatory pain, chronic pruritus, drug-induced allergic-like reactions, metabolic syndrome, esophageal reflux, asthma, cough, migraine, chronic provoked urticaria, chronic pruritus syndrome, acute pruritus, nodular pruritus, osteoarthritis, pseudo-allergic reaction or contact urticaria, etc[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 2767111-67-9
-
分子量 491.44
-
分子式 C23H21F4N5O3
-
SMILES
FC1([C@@H](C2=CC=[N+]([O-])C=C2)CN(CC1)[C@@H](C)C(NC3=NC=C(OC4=C(C=C(C=C4)F)F)N=C3)=O)F
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)