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Nek2-IN-6 (Compound 28e) is a potent never in mitosis (NIMA) related kinase 2 (Nek2) inhibitor.

For research use only. We do not sell to patients.

Nek2-IN-6 Chemical Structure

Nek2-IN-6 Chemical Structure

CAS No. : 2410376-96-2

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Nek2-IN-6 Related Antibodies

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Description

Nek2-IN-6 (Compound 28e) is a potent never in mitosis (NIMA) related kinase 2 (Nek2) inhibitor[1].

IC50 & Target

Nek2[1]
In Vitro

Nek2-IN-6 (Compound 28e) (0-30 μM; 72 h) inhibits tumor cells proliferation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Nek2-IN-6 Related Antibodies

Cell Proliferation Assay[1]

Cell Line: MGC-803, Hep-3B, BEL-7402, HCT-116
Concentration: 0-30 μM
Incubation Time: 72 h
Result: Inhibited cell proliferation with IC50s of 0.038, 1.25, 10.44 and 0.48 μM against MGC-803, Hep-3B, BEL-7402 and HCT-116 cells, respectively.
Molecular Weight

666.71

Formula

C33H33F3N6O4S
CAS No.
SMILES

CC(C1=CC=CC=C1C(F)(F)F)OC2=C(SC(C3=CN=C4C=C(C=CN34)C5=CN(N=C5)CC6CN(C6)C(OC(C)(C)C)=O)=C2)C(N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Nek2-IN-6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nek2-IN-62410376-96-2OthersNek2NIMAnever in mitosis related kinase 2MGC-803Hep-3BBEL-7402HCT-116Inhibitorinhibitorinhibit

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