Nevadistinel
Nevadistinel (NYX-458; NYX-3054) is a positive allosteric modulator of N-methyl-D-aspartate (NMDA) receptor. Nevadistinel can be used to inhibit cognitive impairment associated with neurodegenerative diseases, such as mild cognitive impairment, mild Alzheimer's disease, Parkinson's disease, Lewy body disease.
For research use only. We do not sell to patients.
- CAS No.: 2181816-92-0
- Formula: C15H18N2O3
- Molecular Weight:274.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All iGluR Isoforms
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Biological Activity
NMDA receptor[1]
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 2181816-92-0
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Molecular Weight 274.32
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Formula C15H18N2O3
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SMILES
O=C1[C@@]2(CC(NCC2)=O)CN1CC3=CC=C(C=C3)OC
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Synonyms
NYX-458; NYX-3054
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)