10-Hydroxystearic acid
Based on 1 Customer Validation
10-Hydroxystearic acid (10-HSA) is a PPARα agonist. 10-Hydroxystearic acid stimulates collagen synthesis. 10-Hydroxystearic acid is an anti-aging agent and reduces the appearance of pores and hyperpigmented lesions.
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 638-26-6
- Formula: C18H36O3
- Molecular Weight:300.48
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 638-26-6
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Appearance Solid
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Molecular Weight 300.48
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Formula C18H36O3
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Color White to off-white
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SMILES
CCCCCCCCC(O)CCCCCCCCC(O)=O
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Synonyms
10-HSA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (332.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3280 mL | 16.6400 mL | 33.2801 mL | 83.2002 mL |
| 5 mM | 0.6656 mL | 3.3280 mL | 6.6560 mL | 16.6400 mL | |
| 10 mM | 0.3328 mL | 1.6640 mL | 3.3280 mL | 8.3200 mL | |
| 15 mM | 0.2219 mL | 1.1093 mL | 2.2187 mL | 5.5467 mL | |
| 20 mM | 0.1664 mL | 0.8320 mL | 1.6640 mL | 4.1600 mL | |
| 25 mM | 0.1331 mL | 0.6656 mL | 1.3312 mL | 3.3280 mL | |
| 30 mM | 0.1109 mL | 0.5547 mL | 1.1093 mL | 2.7733 mL | |
| 40 mM | 0.0832 mL | 0.4160 mL | 0.8320 mL | 2.0800 mL | |
| 50 mM | 0.0666 mL | 0.3328 mL | 0.6656 mL | 1.6640 mL | |
| 60 mM | 0.0555 mL | 0.2773 mL | 0.5547 mL | 1.3867 mL | |
| 80 mM | 0.0416 mL | 0.2080 mL | 0.4160 mL | 1.0400 mL | |
| 100 mM | 0.0333 mL | 0.1664 mL | 0.3328 mL | 0.8320 mL |