Daunomycinone
Based on 1 Customer Validation
Daunomycinone (NSC-109351) is a metabolite of Daunomycin (HY-13062A) and anticancer intermediate. Daunomycinone binds to nucleic acids synergistically with metal ions. Daunomycinone can be used in the research of leukemia.
For research use only. We do not sell to patients.
- Purity: 98.89%
- CAS No.: 21794-55-8
- Formula: C21H18O8
- Molecular Weight:398.36
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 21794-55-8
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Appearance Solid
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Molecular Weight 398.36
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Formula C21H18O8
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Color Orange to red
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SMILES
O=C(C1=CC=CC(OC)=C1C2=O)C3=C2C(O)=C4[C@H](C[C@](C(C)=O)(CC4=C3O)O)O
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Synonyms
NSC-109351
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (251.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (647 KB)
- English - EN (647 KB)
- Français - FR (647 KB)
- Deutsch - DE (647 KB)
- Norwegian - NO (647 KB)
- Español - ES (647 KB)
- Swedish - SV (647 KB)
- Italian - IT (647 KB)
- Korean - KR (647 KB)
- Portuguese - PT (647 KB)
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Handling Instructions (2659 KB)
References
[1]. Herman EH, et al. Modification of some of the toxic effects of daunomycin (NSC-82,151) by pretreatment with the antineoplastic agent ICRF 159 (NSC-129,943). Toxicol Appl Pharmacol. 1974 Mar;27(3):517-26. [Content Brief]
[2]. Tan C, et al. Daunomycin, an antitumor antibiotic, in the treatment of neoplastic disease. Clinical evaluation with special reference to childhood leukemia. Cancer. 1967 Mar;20(3):333-53. [Content Brief]
[4]. Aligiannis N, et al. Synthesis and cytotoxic activity of a new potent daunomycinone derivative. Bioorg Med Chem Lett. 2002 Dec 16;12(24):3505-7. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5103 mL | 12.5515 mL | 25.1029 mL | 62.7573 mL |
| 5 mM | 0.5021 mL | 2.5103 mL | 5.0206 mL | 12.5515 mL | |
| 10 mM | 0.2510 mL | 1.2551 mL | 2.5103 mL | 6.2757 mL | |
| 15 mM | 0.1674 mL | 0.8368 mL | 1.6735 mL | 4.1838 mL | |
| 20 mM | 0.1255 mL | 0.6276 mL | 1.2551 mL | 3.1379 mL | |
| 25 mM | 0.1004 mL | 0.5021 mL | 1.0041 mL | 2.5103 mL | |
| 30 mM | 0.0837 mL | 0.4184 mL | 0.8368 mL | 2.0919 mL | |
| 40 mM | 0.0628 mL | 0.3138 mL | 0.6276 mL | 1.5689 mL | |
| 50 mM | 0.0502 mL | 0.2510 mL | 0.5021 mL | 1.2551 mL | |
| 60 mM | 0.0418 mL | 0.2092 mL | 0.4184 mL | 1.0460 mL | |
| 80 mM | 0.0314 mL | 0.1569 mL | 0.3138 mL | 0.7845 mL | |
| 100 mM | 0.0251 mL | 0.1255 mL | 0.2510 mL | 0.6276 mL |
Daunomycinone Related Classifications
HY-114658 Related Classifications
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