WSD0628
Based on 1 Customer Validation
WSD0628 is a brain penetrant and potent ATM inhibitor with profound radiosensitizing effect.
For research use only. We do not sell to patients.
- Purity: 99.43%
- CAS No.: 2765448-96-0
- Formula: C23H23F2N5O2
- Molecular Weight:439.46
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
WSD0628 significantly increased the radiosensitivity of U251 cells in clonogenic survival assays (0 nM vs. 30 nM at 5Gy, p<0.01)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 2765448-96-0
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Appearance Solid
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Molecular Weight 439.46
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Formula C23H23F2N5O2
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Color Off-white to light yellow
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SMILES
CN(C(N1[C@H]2C(F)(F)CN(C)CC2)=O)C3=C1C4=CC(C5=CN=C(OC)C=C5)=CC=C4N=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)