NLRP3 modulator 7 TFA
NLRP3 modulator 7 (Compound 17B) TFA is a NLRP3 inflammasome modulator. NLRP3 modulator 7 TFA inhibits LPS (HY-D1056)-induced IL-1β release in fresh human whole blood. NLRP3 modulator 7 TFA can be used in studies related to NLRP3 inflammasome activation and innate immune signaling.
For research use only. We do not sell to patients.
- Formula: C21H23F6N3O4
- Molecular Weight:495.42
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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NLRP3 inflammasome |
IL-1b < 500 nM (IC50) |
In Vitro
NLRP3 modulator 7 (Compound 17B) TFA inhibits IL-1β production in immune cells stimulated via NLRP3 inflammasome activation with an IC50 < 500 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 495.42
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Formula C21H23F6N3O4
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SMILES
OC1=C(C2=C(C=C(N=N2)[C@@H]([C@@]3([H])CN(CCC3)C)O)C)C=CC(C(F)(F)F)=C1.OC(C(F)(F)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NLRP3 modulator 7 TFA Related Classifications
HY-160757A Related Classifications
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