NU9056 (Standard)
NU9056 (Standard) is the analytical standard of NU9056 (HY-110127). This product is intended for research and analytical applications. NU9056 is a potent and selective Tip60 (KAT5) histone acetyltransferase inhibitor with an of 2 μM. NU9056 shows >16-fold selectivity for Tip60 over PCAF, p300 and GCN5. NU9056 induces apoptosis of prostate cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 1450644-28-6
- Formula: C6H4N2S4
- Molecular Weight:232.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1450644-28-6
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Molecular Weight 232.37
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Formula C6H4N2S4
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SMILES
C1(SSC2=CC=NS2)=CC=NS1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Kelly Coffey, et al. Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. PLoS One. 2012;7(10):e45539. [Content Brief]
[2]. Klotilda Narkaj, et al. Blocking H2A.Z Incorporation via Tip60 Inhibition Promotes Systems Consolidation of Fear Memory in Mice. eNeuro. 2018 Nov 8;5(5):ENEURO.0378-18.2018. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)