NVP-QBE170
NVP-QBE170 is a selective Epithelial sodium channel (ENaC) inhibitor with an IC50 of 57.5 nM. NVP-QBE170 potently inhibits ENaC function in HBECs and shows a longer duration of action. NVP-QBE170 significantly attenuates ENaC activity in the airways of guinea pig models. NVP-QBE170 can be used for hyperkalaemia research.
For research use only. We do not sell to patients.
- CAS No.: 1080018-61-6
- Formula: C30H36Cl2N16O4
- Molecular Weight:755.62
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
Chemical Information
-
CAS No. 1080018-61-6
-
Molecular Weight 755.62
-
Formula C30H36Cl2N16O4
-
SMILES
O=C(C1=NC(Cl)=C(N)N=C1N)NC(NC2CCN(CC2)C(C3=CC=C(C(N4CCC(CC4)NC(NC(C5=NC(Cl)=C(N)N=C5N)=O)=N)=O)C=C3)=O)=N
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NVP-QBE170 Related Classifications
HY-177311 Related Classifications
Powered by Bioz