2. Apoptosis
  3. c-Myc
  4. NY2267

NY2267 

Cat. No.: HY-134975 Purity: 99.34%
COA Handling Instructions

NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM. NY2267 inhibits Myc- and Jun-induced transcriptional activation.

For research use only. We do not sell to patients.

NY2267 Chemical Structure

NY2267 Chemical Structure

CAS No. : 886053-73-2

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 330 In-stock
Estimated Time of Arrival: December 31
Oil + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 330 In-stock
Estimated Time of Arrival: December 31
Oil
5 mg USD 300 In-stock
Estimated Time of Arrival: December 31
10 mg USD 480 In-stock
Estimated Time of Arrival: December 31
25 mg USD 950 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1450 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2250 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM. NY2267 inhibits Myc- and Jun-induced transcriptional activation[1].

In Vitro

NY2267 strongly inhibits oncogenic transformation induced by Myc[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

637.76

Appearance

Oil

Formula

C38H43N3O6
CAS No.
SMILES

O=C(OC(C)(C)C)COC1=CC=C2C=C(C(N(CC3=CC=C(OC)C=C3)C(C4=NC=CC=C4)=O)C(NC5CCCCC5)=O)C=CC2=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (392.00 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5680 mL 7.8399 mL 15.6799 mL
5 mM 0.3136 mL 1.5680 mL 3.1360 mL
10 mM 0.1568 mL 0.7840 mL 1.5680 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (3.26 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

NY2267886053-73-2NY 2267NY-2267c-MycMycMaxinteractionInhibitorinhibitorinhibit

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