O-Methylnotoptol
O‑Methylnotoptol is a Coumarin (HY-N0709) isolated from the roots and rhizomes of Notopterygium incisum. O‑Methylnotoptol inhibits LPS‑induced nitric oxide production in RAW 264.7 murine macrophages with an IC50 value of 23.9 μM.
For research use only. We do not sell to patients.
- CAS No.: 88206-50-2
- Formula: C22H24O5
- Molecular Weight:368.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
23.9 μM
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Inhibition of LPS-induced nitric oxide production in murine macrophage RAW 264.7 cells, based on triplicate experiments.
Inhibition of LPS-induced nitric oxide production in murine macrophage RAW 264.7 cells, based on triplicate experiments.
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30291965 |
O-Methylnotoptol (compound 8) moderately inhibits LPS-induced nitric oxide production in RAW 264.7 cells with an IC50 of 23.9 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 88206-50-2
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Molecular Weight 368.43
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Formula C22H24O5
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SMILES
O(C/C=C(/C/C=C/C(OC)(C)C)\C)C=1C2=C(C=C3C1C=CO3)OC(=O)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
O-Methylnotoptol Related Classifications
HY-187049 Related Classifications
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