pan-KRAS-IN-16
pan-KRAS-IN-16 (Compound 3344) is an anti-RAS small molecule derived from an intracellular antibody fragment with pan-RAS-effector protein-protein interaction inhibitor properties. pan-KRAS-IN-16 binds to a hydrophobic pocket near to the effector-binding switch regions of RAS. pan-KRAS-IN-16 prevents endogenous RAS-dependent signaling in tumor cell lines.
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- CAS. Nr.: 2368246-78-8
- Formel: C24H26N2O3
- Molecular Weight:390.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
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KRas G12D |
H-Ras |
Ras |
Chemical Information
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CAS. Nr. 2368246-78-8
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Molecular Weight 390.47
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Formel C24H26N2O3
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SMILES
CN(C)CC1=CC(NC2=CC=C(C3=C4OCCOC4=CC=C3)C=C2OC)=CC=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
pan-KRAS-IN-16 Related Classifications
HY-164645 Related Classifications
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