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Plozasiran sodium

(Synonyms: ARO-APOC3 sodium)
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Plozasiran sodium is an siRNA targeting APOC3 for the study of mixed hyperlipidemia.

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  • Reinheit: 99.00%
  • CAS. Nr.: 2379776-41-5
  • Molecular Weight:15618.77 (free acid)
  • Speicherung:

    -20°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Plozasiran sodium Chemical Structure
    Plozasiran sodium Chemical Structure
CAS. Nr.: 2379776-41-5
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  • Plozasiran sodium Chemical Structure
    Plozasiran sodium Chemical Structure RNA, ([1'-de(6-amino-9H-purin-9-yl)]dA-(5'→5')-sp-Am-Cm-Gm-Gm-Gm-Am-Cm-Am- (2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)A-Um-Um-Cm-Um-CmAm-Gm-Um-Im-Am-(3'→3')-sp-[1'-de(6-amino-9H-purin-9-yl)]dA), 3'-[O-[cis-4- [(3S,8S)-17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,8-bis[[[2-[2-[[2- (acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]amino]carbonyl]- 1,6,11-trioxo-15-oxa-2,7,12-triazaheptadec-1-yl]cyclohexyl] hydrogen phosphorothioate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)C-sp-Am-sp-(2'- deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)G-Am-Gm-Am-Am-Um-(2'-deoxy-2'- fluoro)A-Cm-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)U-Cm-(2'-deoxy-2'-fluoro)CCm-(2'-deoxy-2'-fluoro)G-sp-Um) (1:1) sodium salt (1:23:1:20)
    1/16
  • RNA, ([1'-de(6-amino-9H-purin-9-yl)]dA-(5'→5')-sp-Am-Cm-Gm-Gm-Gm-Am-Cm-Am- (2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)A-Um-Um-Cm-Um-CmAm-Gm-Um-Im-Am-(3'→3')-sp-[1'-de(6-amino-9H-purin-9-yl)]dA), 3'-[O-[cis-4- [(3S,8S)-17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,8-bis[[[2-[2-[[2- (acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]amino]carbonyl]- 1,6,11-trioxo-15-oxa-2,7,12-triazaheptadec-1-yl]cyclohexyl] hydrogen phosphorothioate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)C-sp-Am-sp-(2'- deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)G-Am-Gm-Am-Am-Um-(2'-deoxy-2'- fluoro)A-Cm-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)U-Cm-(2'-deoxy-2'-fluoro)CCm-(2'-deoxy-2'-fluoro)G-sp-Um) (1:1) sodium salt (1:23:1:20)