1. Anti-infection
  2. Antibiotic Bacterial Fungal
  3. Polyhexamethyleneguanidine hydrochloride

Polyhexamethyleneguanidine hydrochloride  (Synonyms: PHMGH)

Cat. No.: HY-W392026
Handling Instructions Technical Support

Polyhexamethyleneguanidine (PHMGH) hydrochloride is a positively charged polymer with broad-spectrum antimicrobial activity. It exerts its antibacterial effects by binding to the cell membranes of bacteria and fungi, disrupting membrane integrity. Polyhexamethyleneguanidine hydrochloride can be applied in studies related to disinfection, water treatment, pesticides, and other fields[2]

For research use only. We do not sell to patients.

Polyhexamethyleneguanidine hydrochloride

Polyhexamethyleneguanidine hydrochloride Chemical Structure

CAS No. : 57028-96-3

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Description

Polyhexamethyleneguanidine (PHMGH) hydrochloride is a positively charged polymer with broad-spectrum antimicrobial activity. It exerts its antibacterial effects by binding to the cell membranes of bacteria and fungi, disrupting membrane integrity. Polyhexamethyleneguanidine hydrochloride can be applied in studies related to disinfection, water treatment, pesticides, and other fields[1][2]

Formula

(C6H16N2.CH5N3.HCl)x

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N=C(NCCCCCCC)NC.[H]Cl.[F,Cl,Br,I].[n]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

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Polyhexamethyleneguanidine hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Polyhexamethyleneguanidine hydrochloride
Cat. No.:
HY-W392026
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