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Cat. No.: HY-155560

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Pomalidomide-C7-NH2

(Synonyms: Pomalidomide 4'-alkylC7-amine)

Pomalidomide-C7-NH2 (Pomalidomide 4'-alkylC7-amine) (Compound 24g) is an E3 Ligase Ligand-Linker Conjugates consisting of Pomalidomide (HY-10984) and a linker. Pomalidomide-C7-NH2 can be used for synthesis of PROTACs.

For research use only. We do not sell to patients.

CAS No.: 2093387-55-2
Formula: C₂₀H₂₆N₄O₄
Molecular Weight:386.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Pomalidomide-C7-NH2 Chemical Structure

CAS No.: 2093387-55-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

CAS No. 2093387-55-2
Molecular Weight 386.44
Formula C₂₀H₂₆N₄O₄
SMILES

O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCCCCCCN)=CC=C3)=O)=O
Synonyms

Pomalidomide 4'-alkylC7-amine
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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