PROTAC BTK Degrader-4
PROTAC BTK Degrader-4 (compound 15) is a potent PROTAC Bruton's tyrosine kinases (BTK) degrader (DC50 < 100 nM) with little immunomodulatory imide drug (IMiD) activity (DC50 = 0.345 μM, Dmax = 27.4%). PROTAC BTK Degrader-4 can be used for cancers, autoimmune diseases, and inflammatory diseases that are mediated by BTK.
(Pink: Btk ligand (HY-170324); Blue: Cereblon E3 ligase ligand; Black: linker).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2893795-12-3
- Fòrmula: C42H54N12O5
- Peso molecular:806.96
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 2893795-12-3
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Peso molecular 806.96
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Fòrmula C42H54N12O5
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SMILES
O=C(C1=NC=C(N2C[C@H](N3CCN(C)C3=O)CCC2)N=C1NC4=CC=C(C5CCN(CC6CCN(C7=CC=C(C(NC(CC8)C(NC8=O)=O)=O)N=C7)CC6)CC5)C=C4)N
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC BTK Degrader-4 Related Classifications
HY-128408 Related Classifications
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