2. PROTAC
  3. Ligands for E3 Ligase
  4. (R,S,S)-VH032

(R,S,S)-VH032 is Ligand for E3 Ligase used in the synthesis of PROTACs. VH032 is a VHL ligand and VHL/HIF-1α interaction inhibitor that recruits von Hippel-Lindau (VHL) proteins. (R,S,S)-VH032 synthesizes the tau-targeting small molecule PROTAC C004019 (HY-138669).

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(R,S,S)-VH032

(R,S,S)-VH032 화학구조

CAS No. : 2230826-33-0

사이즈 가격 재고 수량
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

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This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of (R,S,S)-VH032:

(R,S,S)-VH032 Related Antibodies

Top Publications Citing Use of Products

View All Ligands for E3 Ligase Isoform Specific Products:

View All Isoforms
von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1 TRIM21 NEURL1B KLHL41

  • Biological Activity

  • 순도&문서

  • References

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제품 설명

(R,S,S)-VH032 is Ligand for E3 Ligase used in the synthesis of PROTACs. VH032 is a VHL ligand and VHL/HIF-1α interaction inhibitor that recruits von Hippel-Lindau (VHL) proteins. (R,S,S)-VH032 synthesizes the tau-targeting small molecule PROTAC C004019 (HY-138669)[1].

IC50 & Target

VHL

 

분자량

430.56

화학식

C22H30N4O3S
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

CC1=C(SC=N1)C(C=C2)=CC=C2CNC([C@@H]3N(C[C@H](C3)O)C([C@@H](N)C(C)(C)C)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
순도&문서

Purity: 98.99%

SDS (393 KB)

COA (252 KB) HNMR (120 KB) LCMS (144 KB)

Handling Instructions (2659 KB)
References
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(R,S,S)-VH032 Related Classifications

  • 몰농도 계산기

  • 농도 희석 계산기

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R,S,S)-VH0322230826-33-0Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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Inquiry Information

상품명:
(R,S,S)-VH032
Cat. No.:
HY-138678
수량:
MCE Japan Authorized Agent:

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SAFETY DATA SHEET (SDS)

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