RAYZ-8009
RAYZ-8009 is a DOTA (HY-W053583)-modified macrocyclic peptide with high affinity for GPC3. The radiolabeled form of RAYZ-8009, [68Ga]Ga-RAYZ-8009, is used for PET imaging studies of hepatocellular carcinoma.
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- CAS. Nr.: 3066113-06-9
- Formel: C91H119N17O22S
- Molecular Weight:1835.08
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biologische Aktivität
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Chemical Information
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Alle Radionuclide-Drug Conjugates (RDCs) Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
RDC Peptide |
In Vitro
RAYZ-8009 shows high binding affinity for mouse, canine, and cynomolgus monkey GPC3 proteins, and exhibits potent cell binding and efficient internalization in GPC3-positive HepG2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 3066113-06-9
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Molecular Weight 1835.08
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Formel C91H119N17O22S
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SMILES
CN(C([C@@H](NC([C@](NC([C@](NC([C@@H](NC([C@@H](N(C([C@@H](NC([C@](N(C([C@@H](N(C(CSC[C@H](N(C([C@@H](NC(CNC1=O)=O)CC2=CN=C(C3=CC=CC=C3)C=C2)=O)C)C(N)=O)=O)C)CCCCN)=O)C)([H])[C@@H](C)CC)=O)CC(O)=O)=O)C)CCC(N)=O)=O)CC4=CC=C(C=C4)C(O)=O)=O)([H])[C@@H](C)OC)=O)([H])[C@@H](C)CC)=O)CC5=CC=C(C=C5)OCC(O)=O)=O)[C@H]1CC6=CC7=C(C=CN=C7)C=C6
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
RAYZ-8009 Related Classifications
HY-P12340 Related Classifications
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