RdRP-IN-8
RdRP-IN-8 (compound 45) is an anti-influenza virus compound. RdRP-IN-8 inhibits viral RNA-dependent RNA polymerase (RdRP) activity by disrupting heterodimerization of PA and PB1 subunits (EC50=0.13 μM).
For research use only. We do not sell to patients.
- Formula: C23H21N3O6S
- Molecular Weight:467.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
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RNA Polymerase |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | CC50 |
>40 μM
Compound: 45
|
Cytotoxicity against human A549 cells
Cytotoxicity against human A549 cells
|
[PMID: 39153334] |
| HEK-293T | CC50 |
>50 μM
Compound: 45
|
Cytotoxicity against HEK293T cells incubated for 48 hrs by MTT assay
Cytotoxicity against HEK293T cells incubated for 48 hrs by MTT assay
|
[PMID: 39153334] |
| MDCK | CC50 |
224 μM
Compound: 45
|
Cytotoxicity against MDCK cells incubated for 48 hrs by MTT assay
Cytotoxicity against MDCK cells incubated for 48 hrs by MTT assay
|
[PMID: 39153334] |
Chemical Information
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Molecular Weight 467.49
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Formula C23H21N3O6S
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SMILES
O=C(C1=C(O)C=C([N+]([O-])=O)C=C1)NC(S2)=C(C(NC3=CC=CC=C3O)=O)C4=C2CCCCC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)