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Cat. No.: HY-107409A

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rel-GNE 5729

rel-GNE 5729 is a relative configuration of GNE 5729 (HY-107409). GNE 5729 is a GluN2A-selective positive allosteric modulator.

For research use only. We do not sell to patients.

CAS No.: 2088424-87-5
Formula: C₁₇H₁₀Cl₂F₃N₅O
Molecular Weight:428.20

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Please store the product under the recommended conditions in the Certificate of Analysis.

rel-GNE 5729 Chemical Structure

CAS No.: 2088424-87-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

rel-GNE 5729 is a relative configuration of GNE 5729 (HY-107409). GNE 5729 is a GluN2A-selective positive allosteric modulator^[1].

All iGluR Isoforms :

Chemical Information

CAS No. 2088424-87-5
Molecular Weight 428.20
Formula C₁₇H₁₀Cl₂F₃N₅O
SMILES

ClC1=C([C@H]2[C@H](C#N)C2)N3C(C=C1)=NC(CN4N=C(C(F)(F)F)C=C4Cl)=CC3=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Villemure E, et al. GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. ACS Med Chem Lett. 2016 Oct 31;8(1):84-89. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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rel-GNE 5729

All iGluR Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

rel-GNE 5729 Related Classifications

HY-107409A Related Classifications

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