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Cat. No.: HY-N19904

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Rhodomyrtosone D

Rhodomyrtosone D is a natural α-glucosidase and BCL-2 inhibitor. Rhodomyrtosone D exhibits an IC₅₀ of 110.45 μg/mL against α-glucosidase derived from Saccharomyces cerevisiae. Rhodomyrtosone D interferes with carbohydrate digestion, interacts with specific BCL-2 amino acid residues, and reduces postprandial blood glucose levels. Rhodomyrtosone D can be used in the research of diabetes and breast cancer.

For research use only. We do not sell to patients.

CAS No.: 1079988-19-4
Formula: C₂₅H₃₂O₆
Molecular Weight:428.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Rhodomyrtosone D Chemical Structure

CAS No.: 1079988-19-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
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Bioz

Biological Activity

Description

IC₅₀ & Target^[1]^[2]

Bcl-2

α-Glucosidase

110.45 μg/mL (IC₅₀)

All Bcl-2 Family Isoforms :

In Vitro

Rhodomyrtosone D (0.24-30.77 µg/mL; 5 min preincubation, 30 min incubation with enzyme) inhibits α-glucosidase from Saccharomyces cerevisiae with an IC₅₀ of 110.45 µg/mL, demonstrating stronger inhibitory activity than acarbose^[1].
Rhodomyrtosone D shows in silico potential as an inhibitor of human BCL-xL (PDB 2w3l), with a docking score of -80.0479, and shares 50% of key interacting residues with the native ligand^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1079988-19-4
Molecular Weight 428.52
Formula C₂₅H₃₂O₆
SMILES

CC([C@@]12[C@@](C3=C(C(C)(C(C(C)(C3=O)C)=O)C)O2)([H])C4=C(C(C)(C(C(C)(C4=O)C)=O)C)O1)C
Structure Classification
- Others
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Ferlinahayati, et al. α-Glucosidase Inhibitory and A Leptospermone Derivative from Rhodomyrtus tomentosa. Indonesian Journal of Chemistry. 2019;19(3):719-726.

[2]. Hadi S, et al. Screening of Rhodomyrtus tomentosa (Aiton) Wight (Karamunting) Compounds that Have the Potential for Breast Cancer. Hydrogen: Jurnal Kependidikan Kimia. 2023;11(2):158-165.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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Rhodomyrtosone D

All Bcl-2 Family Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Rhodomyrtosone D Related Classifications

HY-N19904 Related Classifications