1. Metabolic Enzyme/Protease
  2. Mitochondrial Metabolism
  3. S3QEL-2

S3QEL-2 

Cat. No.: HY-110282 Purity: 98.07%
Handling Instructions

S3QEL-2, a suppressor of superoxide production from mitochondrial complex III, potently and selectively suppresses site IIIQo superoxide production (IC50=1.7 μM). S3QEL-2 does not affect oxidative phosphorylation, and normal electron flux. S3QEL-2 inhibits HIF-1α accumulation.

For research use only. We do not sell to patients.

S3QEL-2 Chemical Structure

S3QEL-2 Chemical Structure

CAS No. : 890888-12-7

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 55 In-stock
Estimated Time of Arrival: December 31
Solid
5 mg USD 50 In-stock
Estimated Time of Arrival: December 31
10 mg USD 80 In-stock
Estimated Time of Arrival: December 31
25 mg USD 150 In-stock
Estimated Time of Arrival: December 31
50 mg USD 250 In-stock
Estimated Time of Arrival: December 31
100 mg USD 400 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

S3QEL-2, a suppressor of superoxide production from mitochondrial complex III, potently and selectively suppresses site IIIQo superoxide production (IC50=1.7 μM). S3QEL-2 does not affect oxidative phosphorylation, and normal electron flux. S3QEL-2 inhibits HIF-1α accumulation[1].

In Vitro

S3QELs-2 protects against ROS-induced, JNK-mediated cell stress in pancreatic β-cells and S3QEL-2 strongly mitigates the oxidative stress-induced apoptosis that limits the yield of functional β-cells from intact islets[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

323.44

Formula

C₁₉H₂₅N₅

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (154.59 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0918 mL 15.4588 mL 30.9176 mL
5 mM 0.6184 mL 3.0918 mL 6.1835 mL
10 mM 0.3092 mL 1.5459 mL 3.0918 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 98.07%

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Product Name:
S3QEL-2
Cat. No.:
HY-110282
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