1. Metabolic Enzyme/Protease
  2. Mitochondrial Metabolism
  3. S3QEL-2

S3QEL-2 

Cat. No.: HY-110282
Handling Instructions

S3QEL-2, a suppressor of superoxide production from mitochondrial complex III, potently and selectively suppresses site IIIQo superoxide production (IC50=1.7 μM). S3QEL-2 does not affect oxidative phosphorylation, and normal electron flux. S3QEL-2 inhibits HIF-1α accumulation.

For research use only. We do not sell to patients.

S3QEL-2 Chemical Structure

S3QEL-2 Chemical Structure

CAS No. : 890888-12-7

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Description

S3QEL-2, a suppressor of superoxide production from mitochondrial complex III, potently and selectively suppresses site IIIQo superoxide production (IC50=1.7 μM). S3QEL-2 does not affect oxidative phosphorylation, and normal electron flux. S3QEL-2 inhibits HIF-1α accumulation[1].

In Vitro

S3QELs-2 protects against ROS-induced, JNK-mediated cell stress in pancreatic β-cells and S3QEL-2 strongly mitigates the oxidative stress-induced apoptosis that limits the yield of functional β-cells from intact islets[1].

Molecular Weight

323.44

Formula

C₁₉H₂₅N₅

CAS No.

890888-12-7

SMILES

CCCN(CCC)C1=C2C(N(C3=CC=C(C)C(C)=C3)N=C2)=NC=N1

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

S3QEL-2Mitochondrial MetabolismsuperoxideproductionmitochondrialcomplexIIIoxidativephosphorylationelectronfluxInhibitorinhibitorinhibit

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