Sapanisertib (Standard)
Sapanisertib (INK-128; MLN0128; TAK-228) Standard is the analytical standard of Sapanisertib (HY-13328). This product is intended for research and analytical applications. Sapanisertib (INK-128; MLN0128; TAK-228) is an orally active dual mTORC1/mTORC2 inhibitor. Sapanisertib directly and simultaneously inhibits mTORC1/2 activity through competitive binding with ATP, thereby comprehensively blocking downstream processes such as protein and lipid synthesis and cytoskeletal reorganization, consequently suppressing tumor cell proliferation and promoting apoptosis. Sapanisertib is applicable to research on melanoma, ovarian cancer, pulmonary fibrosis, and hematological malignancies.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 1224844-38-5
- Formula: C15H15N7O
- Molecular Weight:309.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1224844-38-5
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Molecular Weight 309.33
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Formula C15H15N7O
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SMILES
NC1=NC=NC2=C1C(C3=CC4=C(C=C3)OC(N)=N4)=NN2C(C)C
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Synonyms
INK-128 (Standard); MLN0128 (Standard); TAK-228 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Sapanisertib (Standard) Related Classifications
HY-13328R Related Classifications
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Keywords
- Sapanisertib (Standard)
- 1224844-38-5
- INK-128 (Standard)
- MLN0128 (Standard)
- TAK-228 (Standard)
- Reference Standards
- mTOR
- Apoptosis
- Akt
- ERK
- CDK
- Ribosomal S6 Kinase (RSK)
- Collagen
- HIF/HIF Prolyl-Hydroxylase
- Wnt
- mTORC1
- S6
- 4EBP-1
- AKT
- embryonic stem cells
- apoptosis
- pulmonary fibrosis
- mTORC2
- PI3K/AKT/mTOR signaling
- melanoma
- Inhibitor
- inhibitor
- inhibit