2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. SARM1-IN-8

SARM1-IN-8 (compound 6) is a competitive SARM1 base-exchange inhibitor. SARM1-IN-8 shows competitive inhibition of SARM1Δ1-27 activity with respect to the NAD+ substrate.

For research use only. We do not sell to patients.

SARM1-IN-8

SARM1-IN-8 Chemical Structure

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SARM1-IN-8 Related Antibodies

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Description

SARM1-IN-8 (compound 6) is a competitive SARM1 base-exchange inhibitor. SARM1-IN-8 shows competitive inhibition of SARM1Δ1-27 activity with respect to the NAD+ substrate[1].

Molecular Weight

916.17

Formula

C33H44ClN11O14P2
SMILES

NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OC[C@H]4[C@H](O)[C@H](O)[C@@H]([N+]5=CC=C(CC6=CC=C(NC(NC7=NC=CC=C7)=O)C=C6)C=C5)O4)([O-])=O)([O-])=O)O3.[NH4+].[NH4+].[Cl-]
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SARM1-IN-8 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SARM1-IN-8Toll-like Receptor (TLR)base-exchange inhibitorNAD+ substrateInhibitorinhibitorinhibit

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HY-179598
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