SB-236057
SB-236057 is an inverse agonist of the 5-HT1B receptor that exhibits strong skeletal teratogenicity in rodents and rabbits. SB-236057 affects gene expression during embryonic development through interference with the Notch signaling pathway and interaction with r-esp1. SB-236057 induces somatic patterning and tail extension defects in rat embryos during early organogenesis.
For research use only. We do not sell to patients.
- CAS No.: 180083-49-2
- Formula: C33H34N4O3
- Molecular Weight:534.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All 5-HT Receptor Isoforms
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Biological Activity
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5-HT1B Receptor |
Chemical Information
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CAS No. 180083-49-2
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Molecular Weight 534.65
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Formula C33H34N4O3
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SMILES
O=C(N1C2=CC3=C(C=C2CC1)OCC34CCN(CC4)CC)C5=CC=C(C6=C(C)C=C(C7=NN=C(C)O7)C=C6)C=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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