Teclozan
Based on 1 Customer Validation
Teclozan (WIN 13146) is an antiprotozoal agent, class in benzylamine derivatives. Teclozan intervenes in the phospholipid metabolism preventes the formation of arachidonic acid. Teclozan acts in the intestinal lumen being effective in Anti-G. intestinalis. Teclozan can be used for the research of protozoan infections.
For research use only. We do not sell to patients.
- Purity: 99.75%
- CAS No.: 5560-78-1
- Formula: C20H28Cl4N2O4
- Molecular Weight:502.26
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Anti-Infection Compound Library
HY-L002
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FDA-Approved Drug Library
HY-L022
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Drug Repurposing Compound Library
HY-L035
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Orally Active Compound Library
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FDA Approved & Pharmacopeial Drug Library
HY-L066
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Antiparasitic Compound library
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Off-patent Drug Library
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MCE Bioactive Compound Library
HY-L001V
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Drug Repurposing Compound Library Plus
HY-L035P
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FDA-Approved Drug Library Plus
HY-L022P
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FDA-Approved Drug Library Mini
HY-L022M
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High-Throughput Bioactive Compound Library
HY-L205
All Parasite Isoforms
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Biological Activity
Chemical Information
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CAS No. 5560-78-1
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Appearance Solid
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Molecular Weight 502.26
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Formula C20H28Cl4N2O4
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Color White to off-white
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SMILES
O=C(N(CC1=CC=C(CN(CCOCC)C(C(Cl)Cl)=O)C=C1)CCOCC)C(Cl)Cl
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Synonyms
WIN 13146
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 62.5 mg/mL (124.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9910 mL | 9.9550 mL | 19.9100 mL | 49.7750 mL |
| 5 mM | 0.3982 mL | 1.9910 mL | 3.9820 mL | 9.9550 mL | |
| 10 mM | 0.1991 mL | 0.9955 mL | 1.9910 mL | 4.9775 mL | |
| 15 mM | 0.1327 mL | 0.6637 mL | 1.3273 mL | 3.3183 mL | |
| 20 mM | 0.0996 mL | 0.4978 mL | 0.9955 mL | 2.4888 mL | |
| 25 mM | 0.0796 mL | 0.3982 mL | 0.7964 mL | 1.9910 mL | |
| 30 mM | 0.0664 mL | 0.3318 mL | 0.6637 mL | 1.6592 mL | |
| 40 mM | 0.0498 mL | 0.2489 mL | 0.4978 mL | 1.2444 mL | |
| 50 mM | 0.0398 mL | 0.1991 mL | 0.3982 mL | 0.9955 mL | |
| 60 mM | 0.0332 mL | 0.1659 mL | 0.3318 mL | 0.8296 mL | |
| 80 mM | 0.0249 mL | 0.1244 mL | 0.2489 mL | 0.6222 mL | |
| 100 mM | 0.0199 mL | 0.0996 mL | 0.1991 mL | 0.4978 mL |
Teclozan Related Classifications
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