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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
INS-1
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "INS-1" in MCE Product Catalog:
Cat. No.: HY-W787880
CAS No.: 208584-51-4
Synonyms: INS(1,2)P2 sodium
Target:
Research Areas:
D-myo-Inositol-1,2-diphosphate (Ins(1,2)P2) sodium is one of the many inositol phosphate (InsP) isomers that could act as small, soluble second messengers in the transmission of cellular signals [1].
Cat. No.: HY-N16465
CAS No.: 97233-06-2
Cat. No.: HY-175385
Synonyms: INS(1)P1 sodium; 1-IP1 sodium salt
Target:
Research Areas:
D-myo-Inositol-1-phosphate (sodium salt) is one of the members in inositol phosphate family of second messengers that play an important role in transmitting cellular signals. D-myo-Inositol-1-phosphate (sodium salt) can be formed by the dephosphorylation of polyphosphate inositols [1] .
Cat. No.: HY-175383
Synonyms: INS(1,2,6)-P3; 1,2,6-IP3
Target:
Research Areas:
D-myo-Inositol-1,2,6-triphosphate (sodium) is one of the members in inositol phosphate family of second messengers that play an important role in transmitting cellular signals. D-myo-Inositol-1,2,6-triphosphate (sodium) can open calcium channels and increase intracellular calcium upon binding to its receptor on the endoplasmic reticulum [1] .
Cat. No.: HY-175387
Synonyms: INS(1,3,4)-P3 sodium; 1,3,4-IP3 sodium
Target:
Research Areas:
D-myo-Inositol-1,3,4-triphosphate (sodium) is one of the inositol oligophosphate isomers implicated in signal transduction. D-myo-Inositol-1,3,4-triphosphate (sodium) acts through the inhibition of Ins(3,4,5,6)-P4 kinase activity to increase cellular level of Ins(3,4,5,6)-P4, thereby inhibiting calcium-activated chloride channels. D-myo-Inositol-1,3,4-triphosphate (sodium) can be regulated by the levels of cytosolic free calcium [1] .
Cat. No.: HY-P84508A
Synonyms: MPP2; TGT3; HFH11; HNF-3; INS-1; MPP-2; PIG29; FKHL16; FOXM1B; HFH-11; TRIDENT; MPHOSPH2
Cat. No.: HY-175385A
Synonyms: INS(1)P1 cyclohexyl ammonium salt; 1-IP1 cyclohexyl ammonium salt
Target:
Research Areas:
D-myo-Inositol-1-phosphate (Ins(1)P1) cyclohexyl ammonium is a member of the inositol phosphate molecular family [1].
Cat. No.: HY-176831
Synonyms: INS(1,5)-P2 sodium; 1,5-IP2 sodium
Target:
Research Areas:
D-myo-Inositol-1,5-diphosphate (Ins(1,5)-P2) sodium is a member of the inositol phosphate molecular family [1].
Cat. No.: HY-164111
CAS No.: 1128096-58-1
Target:
Research Areas:
JNK-IN-17 (Compound 9J) is a selective and potent JNK inhibitor with IC50 values of 0.039, 0.079 μM for JNK1 and JNK3. JNK-IN-17 can inhibit c-Jun phosphorylation with an IC50 of 0.082 μM in Streptozotocin (HY-13753)-infuced INS-1 pancreatic islet β cells. JNK-IN-17 shows inhibition rate ≤ 33% on the four main P450 subtypes (2C9, 2D6, 3A4, 1A2) in human liver microsomes, indicating a relatively low risk of drug interactions. JNK-IN-17 can be used for researches of neurological and metabolic disease, such as Parkinson's disease [1].
Cat. No.: HY-W788039A
Synonyms: INS(1,3,5)P3 sodium; 1,3,5-IP3 sodium
Target:
Research Areas:
D-myo-Inositol-1,3,5-triphosphate (Ins(1,3,5)P3) sodium is a member of the inositol phosphate (InsP) family of second messengers that play a critical role in the transmission of cellular signals [1].
Cat. No.: HY-172570
Synonyms: INS(1,2,3,5,6)-P5 tetrasodium; 1,2,3,5,6-IP5 tetrasodium
Target:
Research Areas:
D-myo-inositol-1,2,3,5-tetraphosphate (Ins(1,2,3,5,6)-P5) tetrasodium is one of the Inositol phosphate isomers and can act as a soluble second messenger to participate in cellular calcium signaling [1].
Cat. No.: HY-P81367
Synonyms: FOXM1; FKHL16, HFH11, MPP2, WIN; Forkhead box protein M1; Forkhead-related protein FKHL16; Hepatocyte nuclear factor 3 forkhead homolog 11 (HFH-11; HNF-3/fork-head homolog 11); M-phase phosphoprotein 2; MPM-2 reactive phosphoprotein 2; Transcription factor Trident; Winged-helix factor from INS-1 cells
Cat. No.: HY-175068
Synonyms: INS(1,3,4,5,6)P5 sodium
Research Areas:
D-myo-Inositol-1,3,4,5,6-pentaphosphate sodium (Ins(1,3,4,5,6)P5 sodium) is a small intracellular signaling molecule. D-myo-Inositol-1,3,4,5,6-pentaphosphate sodium inhibits the PI3K/Akt signaling pathway. D-myo-Inositol-1,3,4,5,6-pentaphosphate sodium inhibits Akt/PKB phosphorylation and kinase activity, inducing apoptosis in cancer cells. D-myo-Inositol-1,3,4,5,6-pentaphosphate sodium inhibits the formation of tubular structures in endothelial cells in an in vitro angiogenesis mouse model. D-myo-Inositol-1,3,4,5,6-pentaphosphate sodium can be used in research on ovarian cancer, lung cancer, breast cancer, and other cancers, as well as in cardiovascular and cerebrovascular diseases such as angiogenesis [1] .
Cat. No.: HY-150135
CAS No.: 85166-31-0
Synonyms: INS(1,4,5)P3
Target:
Cat. No.: HY-W788040
CAS No.: 1246355-68-9
Target:
Research Areas:
Inositol 1,3,4,5-tetraphosphate tetraammonium is an inositol tetraphosphate. Inositol 1,3,4,5-tetraphosphate tetraammonium is metabolically produced from Ins (1,4,5) P3 via 3-kinase, participates in intracellular signal transduction systems, and elevates intracellular calcium concentrations when present [1] .
Cat. No.: HY-P70937
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MINPP1; Inositol (1,3,4,5)-Tetrakisphosphate 3-Phosphatase; Multiple Inositol-Polyphosphate Phosphatase 1; Multiple Inositol Polyphosphate Phosphatase 2; MIPP; INS(1,3,4,5)P(4) 3-Phosphatase; Multiple Inositol Polyphosphate Histidine Phosphatase, 1; HIPER
Species:
Human
Source:
HEK293
Cat. No.: HY-P71854
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MINPP1; Inositol (1,3,4,5)-Tetrakisphosphate 3-Phosphatase; Multiple Inositol-Polyphosphate Phosphatase 1; Multiple Inositol Polyphosphate Phosphatase 2; MIPP; INS(1,3,4,5)P(4) 3-Phosphatase; Multiple Inositol Polyphosphate Histidine Phosphatase, 1; HIPER
Species:
Human
Source:
P. pastoris
Cat. No.: HY-P72197
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FOXM1; Forkhead-Related Protein FKHL16; Prev. FKHL16; HNF-3/Fork-Head Homolog 11; HFH-11; HFH11; MPP2; TGT3; M-Phase Phosphoprotein 2; Forkhead, Drosophila, Homolog-Like 16; Forkhead Box Protein M1; Forkhead Box M1-D; MPHOSPH2; FOXM1A; Trident; FOXM1B; HN
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
