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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
583 Results for "
AGE
" in MedChemExpress (MCE) Product Catalog:
Products (583)
583 Results for "AGE" in MCE Product Catalog:
6
Category:
Human Gut Microbiota Metabolites Natural Products Microorganisms Disease markers Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields
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6
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6
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Forschungsgebiete:
PD146176 (NSC168807), a 15-Lipoxygenase (15-LO) inhibitor, inhibits rabbit reticulocyte 15-LO (Ki=197 nM, IC50=0.54 μM). PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice .
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6 Cited Publications
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XJB-5-131 is a mitochondria-targeted ROS and electron scavenger . XJB-5-131 is a bi-functional antioxidant that comprises a radical scavenger. XJB-5-131 is a synthetic antioxidant that targets mitochondria . XJB-5-131 is an effective ionizing irradiation protector and mitigator of cord blood mononuclear cells (CB MNCs) .
5
5 Cited Publications
Art. -Nr.: HY-N2292
CAS. Nr.: 151870-74-5
Category:
Natural Products Orchidaceae Plants Anoectochilus Disease Research Fields Inflammation/Immunology
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5
5 Cited Publications
4
Category:
Cardiovascular Disease Alkaloids other families Plants Disease Research Fields Isoquinoline Alkaloids
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4
Smurf1-IN-A01 is a Smurf1 inhibitor. Smurf1-IN-A01 has anticancer activity and can be used for the research of osteoporosis and age-related macular degeneration .
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4 Cited Publications
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Pyropheophorbide-a (Ppa) is a photosensitizer used in photodynamic therapy (PDT) for tumors. Pyropheophorbide-a exhibits phototoxic effects on tumor cells, such as cervical cancer cells, and also has anti-lipogenesis activity. Pyropheophorbide-a shows potential for research in the fields of cancer and age-related macular degeneration (AMD). Pyropheophorbide-a derivatives also demonstrate inhibitory activity against tumor cells .
4
Category:
Flavonoids Leguminosae Flavonones Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields Cancer
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3
Category:
Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields
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3
Category:
Natural Products Microorganisms Other Diseases Endogenous metabolite Disease Research Fields
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3
3 Cited Publications
Synonyms: Vitamin K2-7; Vitamin K2(35); Vitamin MK-7
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Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs (orally active), is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 inhibits osteoclast bone resorption in vitro and stimulates bone formation in femoral tissue of aged female rats. Menaquinone-7 has a well-researched potential in the prevention of aging-induced bone degeneration. Menaquinone-7 is also a pharmacological option for activating Gla matrix protein and intervening in the progression of calcific aortic stenosis (CAVS) .
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3 Cited Publications
Synonyms: Catechaldehyde; Protocatechuic aldehyde; Rancinamycin IV
3
3 Cited Publications
3
3 Cited Publications
Art. -Nr.: HY-W013494
CAS. Nr.: 305-84-0
3
Forschungsgebiete:
Neurological Disease Metabolic Disease Inflammation/Immunology
N-tert-Butyl-α-phenylnitrone is a nitrone-based free radical scavenger that forms nitroxide spin adducts. N-tert-Butyl-α-phenylnitrone inhibits COX2 catalytic activity. N-tert-Butyl-α-phenylnitrone has potent ROS scavenging, anti-inflammatory, neuroprotective, anti-aging and anti-diabetic activities, and can penetrate the blood-brain barrier .
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3 Cited Publications
Art. -Nr.: HY-N2072
CAS. Nr.: 27876-94-4
Synonyms: Transcrocetin; trans-Crocetin
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3 Cited Publications
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TH10785 is a DNA glycosylase 1 (OGG1) activator, TH10785 can interact with the phenylalanine-319 and glycine-42 amino acids of OGG1 and increase the enzyme activity, generates β, δ-lyase enzymatic function. TH10785 can control the catalytic activity mediated by a nitrogen base within its molecular structure. TH10785 can be used for the research of various diseases and aging connected with DNA oxidative lesions .
3
3 Cited Publications
Art. -Nr.: HY-W250118
CAS. Nr.: 90989-93-8
Forschungsgebiete:
Cephalin form bovine brain is an orally active phospholipid widely present in organisms.Cephalin form bovine brain participates in the formation of autophagosome membrane as a lipid anchor of autophagy-related protein Atg8/LC3. Cephalin form bovine brain enhances Autophagic flux, promotes cell differentiation, regulates lipid droplet fusion, delays aging, and also affects lipid metabolism and membrane integrity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
