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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
318 Results for "
complete
" in MedChemExpress (MCE) Product Catalog:
Products (318)
318 Results for "complete" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: R-75231; R88021
Áreas de investigación:
Draflazine (R-75231) is a ENT1 inhibitor. Draflazine (R-75231) completely reverses the hypersensitivity in the complete Freund’s adjuvant (CFA) model of mechanical hyperalgesia and the carrageenan inflammation model of thermal and mechanical hyperalgesia .
1
1 Cited Publications
PARP1-IN-11 (compound 49) is a potent PARP1 inhibitor with IC50 value of 0.082 µM. PARP1-IN-11 shows complete inhibition of PARP2 and substantially inhibits PARP3, TNKS1 and TNKS2 .
1
1 Cited Publications
Synonyms: PW0464
Target:
Áreas de investigación:
PW0464, a nanomolar potent complete G protein biased ligand, is a noncatechol D1R agonist, with an EC50 of 5.8 nM (Gs-cAMP) .
1
1 Cited Publications
Referencia número: HY-N3087
No. CAS: 13401-40-6
Target:
1
1 Cited Publications
Referencia número: HY-P9923
No. CAS: 1044511-01-4
Synonyms: MEDI-563; BIW-8405; KHK4563
Target:
Áreas de investigación:
Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma .
1
1 Cited Publications
Referencia número: HY-K0533A
MCE 2× High-Fidelity PCR Master Mix (with Dye) is a new type of ready-to-use high-fidelity PCR amplification master mix.During the reaction, only template and primers need to be added to quickly and efficiently complete the PCR process, reducing the risk of contamination during operation. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
1
Category:
Human Gut Microbiota Metabolites Natural Products Other Diseases Endogenous metabolite Disease Research Fields
Target:
1
1 Cited Publications
Referencia número: HY-P99024
No. CAS: 2229047-91-8
Synonyms: RO7082859; RG-6026
Áreas de investigación:
1
1 Cited Publications
Referencia número: HY-P9923A
No. CAS: 1044511-01-4
Synonyms: MEDI-563 (anti-IL5RA); BIW-8405 (anti-IL5RA); KHK4563 (anti-IL5RA)
Target:
Áreas de investigación:
Benralizumab (anti-IL5RA) (MEDI-563 (anti-IL5RA); BIW-8405 (anti-IL5RA)) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma study .
1
1 Cited Publications
Referencia número: HY-D1565
No. CAS: 2270866-73-2
Referencia número: HY-153808B
No. CAS: 9007-81-2
Target:
Áreas de investigación:
Complete Freund's adjuvant (CFA, 1 mg/ml) is an immunoadjuvant emulsified with antigen that can enhance an animal's immune response to an antigen. Complete Freund's adjuvant (CFA, 1 mg/ml) is also an inducer of the Th1 immune response and a ligand of TLRs. Complete Freund's adjuvant (CFA, 1 mg/ml) contains heat-killed inactive tuberculosis bacilli and consists of a paraffin oil-in-water emulsion. Complete Freund's adjuvant (CFA, 1 mg/ml) stimulates a strong and durable immune response and can be used to induce rheumatoid arthritis in rats, and more .
Target:
Áreas de investigación:
Nomegestrol acetate is an orally active, highly selective progestogen and a progesterone receptor complete agonist. Nomegestrol acetate inhibits ovulation. Nomegestrol acetate is also effective in inhibiting the proliferation of human endometrial cancer RL95-2 cells in vitro and in vivo. Nomegestrol acetate can be used in cancer (especially endometrial cancer) and contraceptive studies .
Target:
Áreas de investigación:
M‑1121 is a covalent and orally active inhibitor of the menin-MLL interaction capable of achieving complete and persistent tumor regression .
Referencia número: HY-N7710
No. CAS: 64284-64-6
Category:
Human Gut Microbiota Metabolites Animals Metabolic Disease Endogenous metabolite Disease Research Fields Steroids
Target:
Referencia número: HY-101000
No. CAS: 101831-36-1
Synonyms: R62690
Clazuril (R62690) has a coccidiocidal effect on the asexual and sexual developmental stages of both Eimeria species, resulting in a complete interruption of the life cycle .
Referencia número: HY-126278
No. CAS: 2375374-15-3
Áreas de investigación:
Z1609609733 (Compound 18) is a non-covalent 3-Phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 1.46 μM. Z1609609733 significantly inhibits serine synthesis and cancer metabolism with complete abrogation of cell proliferation .
Referencia número: HY-10984A
No. CAS: 202271-89-4
Synonyms: (S)-CC-4047
Target:
Áreas de investigación:
(S)-Pomalidomide ((S)-CC-4047) is an angiogenesis-inhibiting drug with growth-inhibitory activity against B-cell tumors. (S)-Pomalidomide can induce complete tumor regression in BurKitt lymphoma cells. (S)-Pomalidomide serves as an immunomodulator with potential applications in inhibiting hematological malignancies .
Referencia número: HY-W797383
No. CAS: 2229723-92-4
Áreas de investigación:
Phthalimidinoglutarimide-6-piperazine is a conjugate of E3 ubiquitin ligase ligand-Linker, which can be used to synthesize complete PROTACs molecules.
Referencia número: HY-P4838
No. CAS: 154765-04-5
Target:
Áreas de investigación:
Referencia número: HY-177691
No. CAS: 325780-75-4
Target:
Áreas de investigación:
CCI17464 is a selective, orally active EP4 partial agonist with a pKi of 7.1. CCI17464 can be used in a Freund's complete adjuvant (FCA) acute rat inflammatory pain model and shows complete reversal of allergic reactions .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
