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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
394 Results for "
monkey FAP
" in MedChemExpress (MCE) Product Catalog:
Products (394)
394 Results for "monkey FAP" in MCE Product Catalog:
3
Forschungsgebiete:
2
2 Cited Publications
Art. -Nr.: HY-P72659A
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FAP; Prolyl Endopeptidase FAP; Fibroblast Activation Protein Alpha; Dipeptidyl Peptidase FAP; Seprase; FAPalpha; DPPIV; SIMP; 170 KDa Melanoma Membrane-Bound Gelatinase; CDNA FLJ60298, Highly Similar To Seprase; Gelatine Degradation Protease FAP; Fibroblast Activation Protein, Alpha; Integral Membrane Serine Protease; Serine Integral Membrane Protease; Post-Proline Cleaving Enzyme; FAPA; Surface-Expressed Protease
Species:
Human
Source:
HEK293
2
2 Cited Publications
Target:
Forschungsgebiete:
UAMC-1110 is a highly potent and selective inhibitor of fibroblast activation protein (FAP) with an IC50 of 3.2 nM. UAMC-1110 also inhibits prolyl oligopeptidase (PREP) with an IC50 of 1.8 μM .
2
2 Cited Publications
Forschungsgebiete:
RO5166017 is an orally active and species-crosses TAAR1 agonist, with Ki values of 1.9 nM, 2.7 nM, 31 nM and 24 nM for mouse, rat, human and cynomolgus monkey, respectively .
2
Target:
Forschungsgebiete:
Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib (GS-9876) inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans .
2
2 Cited Publications
Synonyms: GS-9876 succinate
Target:
Forschungsgebiete:
Lanraplenib succinate (GS-9876 succinate) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib succinate (GS-9876 succinate) inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans .
1
1 Cited Publications
Art. -Nr.: HY-P99269
CAS. Nr.: 216669-97-5
Synonyms: BIBH 1; Anti-Human FAP Recombinant Antibody
1
1
1 Cited Publications
Target:
Forschungsgebiete:
Suc-Gly-Pro-AMC is a fluorescent substrate. Suc-Gly-Pro-AMC is a fibroblast activation protein (FAP) specific substrate. Suc-Gly-Pro-AMC reacts with recombinant porcine prolyl oligopeptidase. Suc-Gly-Pro-AMC can be used to study the activity of FAP, prolyl endopeptidase (PREP). Suc-Gly-Pro-AMC is used in glioma research .
1
1 Cited Publications
Art. -Nr.: HY-P990133
Target:
Forschungsgebiete:
1
1
1 Cited Publications
Art. -Nr.: HY-P77934
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: FAP; Prolyl Endopeptidase FAP; Fibroblast Activation Protein Alpha; Dipeptidyl Peptidase FAP; Seprase; FAPalpha; DPPIV; SIMP; 170 KDa Melanoma Membrane-Bound Gelatinase; CDNA FLJ60298, Highly Similar To Seprase; Gelatine Degradation Protease FAP; Fibroblast Activation Protein, Alpha; Integral Membrane Serine Protease; Serine Integral Membrane Protease; Post-Proline Cleaving Enzyme; FAPA; Surface-Expressed Protease
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Art. -Nr.: HY-W404002
CAS. Nr.: 2505339-54-6
Target:
Forschungsgebiete:
BR102910 is a selective fibroblast activation protein (FAP) inhibitor with the IC50 of 2 nM. BR102910 also inhibits prolyl oligopeptidase (PREP) with the IC50 of 49.00 μM. BR102910 can be used for the researchof type 2
1
1 Cited Publications
Art. -Nr.: HY-B0770
CAS. Nr.: 75887-54-6
Synonyms: β-Arteether; (+)-Arteether; Arteether
1
Target:
Forschungsgebiete:
1
1 Cited Publications
Art. -Nr.: HY-19837
CAS. Nr.: 1478712-37-6
Forschungsgebiete:
BMS-986120 is a first-in-class oral and reversible protease-activated receptor 4 (PAR4) antagonist, with IC50s of 9.5 nM and 2.1 nM in human and monkey blood, respectively. BMS-986120 has potent and selective antiplatelet effects .
1
1 Cited Publications
Target:
Forschungsgebiete:
PF-04856264 is a potent and selective Nav1.7 inhibitor, with IC50s of 28, 131, 19, and 42 nM for human, mouse, cynomolgus monkey and dog Nav1.7, respectively. PF-04856264 has low potency against the rat Nav1.7 channel. PF-04856264 shows analgesic effect .
1
1 Cited Publications
Art. -Nr.: HY-P70039
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CTCF; CFAP108; CCCTC-Binding Factor; FAP108; Transcriptional Repressor CTCF; CCCTC-Binding Factor (Zinc Finger Protein); 11-Zinc Finger Protein; 11 Zinc Finger Transcriptional Repressor; CTCFL Paralog; MRD21
Species:
Human
Source:
E. coli
1
Target:
Forschungsgebiete:
Givosiran (ALN-AS1) is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA. Givosiran downregulates ALAS1 mRNA and prevents accumulation of neurotoxic δ-aminolevulinic acid (ALA) and porphobilinogen (PBG) levels. Givosiran demonstrates potent inhibitory activity against ALAS1 in mouse, rat, and cynomolgus monkey models. Givosiran can be used for the research of acute hepatic porphyria (AHP) .
1
1 Cited Publications
Synonyms: ALN-AS1 sodium
Target:
Forschungsgebiete:
Givosiran (ALN-AS1) sodium is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA. Givosiran sodium downregulates ALAS1 mRNA and prevents accumulation of neurotoxic δ-aminolevulinic acid (ALA) and porphobilinogen (PBG) levels. Givosiran sodium demonstrates potent inhibitory activity against ALAS1 in mouse, rat, and cynomolgus monkey models. Givosiran sodium can be used for the research of acute hepatic porphyria (AHP) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
