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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
79 Results for "
ALT
" in MedChemExpress (MCE) Product Catalog:
Products (79)
79 Results for "ALT" in MCE Product Catalog:
Cat. No.: HY-RS17000
Target:
Research Areas:
Gpt Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gpt gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-106024A
CAS No.: 181069-80-7
Synonyms: ALT711 bromide
Target:
Research Areas:
Alagebrium bromide is an analog of Alagebrium Chloride (HY-106024B), a glucose cross-link blocker. Alagebrium Chloride disrupts glucose cross-links and may improve ventricular and arterial compliance. Alagebrium Chloride improves left ventricular diastolic filling and has the potential to inhibit diastolic heart failure (DHF).
Cat. No.: HY-P3690
CAS No.: 148333-42-0
Target:
Research Areas:
Cat. No.: HY-N6595
CAS No.: 97653-92-4
Category:
Human Gut Microbiota Metabolites Microorganisms Terpenoids Diterpenoids Endogenous metabolite
Target:
Cat. No.: HY-N0158R
CAS No.: 16837-52-8
Cat. No.: HY-W750902
CAS No.: 2714484-46-3
Cat. No.: HY-173293
CAS No.: 2570985-89-4
Target:
Research Areas:
ASK1-IN-8 (Compound 35) is an orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 value of 1.8 nM . In an experimental mouse model of liver injury induced by Acetaminophen (HY-66005), ASK1-IN-8 can significantly reduce the plasma alanine transaminase (ALT) level, protecting the liver . ASK1-IN-8 can be used in research related to liver diseases .
Target:
Reference Standards Environmental Pollutants Biochemical Assay Reagents Apoptosis Aminotransferases (Transaminases) Phosphatase
Research Areas:
Diethyl phthalate (Standard) is the analytical standard of Diethyl phthalate (HY-Y0284). This product is intended for research and analytical applications. Diethyl phthalate is an orally active plasticizer and detergent base. Diethyl phthalate increases the activities of ACP, ALP, SDH, and ALT in liver, muscle, or both tissues. Diethyl phthalate induces dose-dependent mortality and sluggish behavior in freshwater fish. Diethyl phthalate may induce male reproductive toxicity. Diethyl phthalate is added to plastic polymers to help maintain their flexibility .
Cat. No.: HY-Y0284S1
CAS No.: 1817006-92-0
Target:
Isotope-Labeled Compounds Environmental Pollutants Biochemical Assay Reagents Apoptosis Aminotransferases (Transaminases) Phosphatase
Research Areas:
Diethyl phthalate-d10 is the d10 labeled Diethyl phthalate (HY-Y0284). Diethyl phthalate is an orally active plasticizer and detergent base. Diethyl phthalate increases the activities of ACP, ALP, SDH, and ALT in liver, muscle, or both tissues. Diethyl phthalate induces dose-dependent mortality and sluggish behavior in freshwater fish. Diethyl phthalate may induce male reproductive toxicity. Diethyl phthalate is added to plastic polymers to help maintain their flexibility .
Category:
Cat. No.: HY-187638
CAS No.: 192511-71-0
Target:
Research Areas:
ALT-946 is an orally active inhibitor of the advanced glycation end product (AGE) formation pathway. ALT-946 blocks the formation of AGE-protein cross-links, reduces the accumulation of AGE in renal tissues, alleviates increased albuminuria and elevated glomerular filtration rate, prevents glomerulosclerosis, ameliorates medullary tubulointerstitial lesions, and reduces cortical tubular degeneration. ALT-946 can be used in research related to diabetic nephropathy and diabetic cardiovascular diseases .
Cat. No.: HY-W879508
CAS No.: 173026-17-0
Synonyms: BXT-51072
Research Areas:
ALT-2074 (BXT-51071) is an orally active catalytic analogue of glutathione peroxidase. ALT-2074 is an inhibitor of human CYP3A, with its IC50 value ranging from 2.0 to 2.6 μM. ALT-2074 shows only a weak inhibitory effect on CYP3A in vivo, suggesting that it may not significantly affect the metabolism of CYP3A substrate drugs. ALT-2074 can be used to study inflammatory diseases characterized by reactive oxygen species, such as acute coronary syndrome .
Cat. No.: HY-187638A
CAS No.: 727972-45-4
Target:
ALT-946 free base is an orally active inhibitor of the advanced glycation end product (AGE) formation pathway. ALT-946 free base blocks the formation of AGE-protein cross-links, reduces the accumulation of AGE in renal tissues, alleviates increased albuminuria and elevated glomerular filtration rate, prevents glomerulosclerosis, ameliorates medullary tubulointerstitial lesions, and reduces cortical tubular degeneration. ALT-946 free base can be used in research related to diabetic nephropathy and diabetic cardiovascular diseases .
Cat. No.: HY-N15378
CAS No.: 132541-62-9
Target:
Cat. No.: HY-N0442R
CAS No.: 84272-85-5
Synonyms: 4'-O-β-D-Glucosyl-5-O-methylvisamminol (Standard)
Cat. No.: HY-P11841
Target:
Research Areas:
Cat. No.: HY-P702494
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GPT; Glutamate Pyruvate Transaminase 1; Glutamic--Pyruvic Transaminase; Glutamic--Pyruvic Transaminase 1; ALT1; Alanine Aminotransferase 1; GPT1; Alanine Aminotransferase; SGPT; Alanine Transaminase; ALT; AAT1; Glutamic-Pyruvate Transaminase (Alanine Amin
Species:
Human
Source:
E. coli
Cat. No.: HY-P75158
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GPT; Glutamate Pyruvate Transaminase 1; Glutamic--Pyruvic Transaminase; Glutamic--Pyruvic Transaminase 1; ALT1; Alanine Aminotransferase 1; GPT1; Alanine Aminotransferase; SGPT; Alanine Transaminase; ALT; AAT1; Glutamic-Pyruvate Transaminase (Alanine Amin
Species:
Rat
Source:
Sf9 insect cells
Cat. No.: HY-N18019
CAS No.: 189289-77-8
Category:
Xanthones Swertia bimaculata (Sieb. et Zucc.) Hook. f. et Thoms. ex C. B. Clark Gentianaceae Extract Phenols Plants
Target:
Cat. No.: HY-187178
CAS No.: 1966932-74-0
Target:
Research Areas:
KDM2A/7-IN-1 is a lysine demethylase 2A (KDM2A) inhibitor with a human IC50 of 11 nM. KDM2A/7-IN-1 requires co-factor 2-oxoglutarate (2OG) for binding and occupies the H3K36me2 substrate pocket via a dimethylated lysine 36-mimicking group. KDM2A/7-IN-1 represses E2F-regulated genes, induces epithelial-mesenchymal transition, DNA repair, and mTOR pathways in specific cells, and selectively inhibits proliferation of ALT-positive cancer cell lines. KDM2A/7-IN-1 can be used for the research of ALT-positive cancers .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
