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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
169 Results for "
alkylating agent
" in MedChemExpress (MCE) Product Catalog:
Products (169)
169 Results for "alkylating agent" in MCE Product Catalog:
Cat. No.: HY-172314
CAS No.: 2377718-85-7
Research Areas:
ACHM-025 is a prodrug, which is selectively activated by AKR1C3 to a nitrogen mustard DNA alkylating agent. ACHM-025 can be used for the research of cancer, such as leukemia .
Cat. No.: HY-W587524
CAS No.: 22788-18-7
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Carboxyphosphamide is an inactive metabolite of the alkylating agent Cyclophosphamide (HY-17420) .
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Porfiromycin (N-Methylmitomycin C) is a bioreductive alkylating agent that preferentially kill hypoxic tumor cells relative to other aerobic counterparts .
Cat. No.: HY-17419S1
CAS No.: 1189701-13-0
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Mitobronitol (Myelobromol; DBM) is a brominated analog of mannitol, also known as an anticancer agent that is classified as an alkylating agent. Mitobronitol has potential for myelosuppression associated with significantly decreased risk for several complications of allogeneic bone marrow transplantation in accelerated chronic granulocytic leukemia .
Cat. No.: HY-101150
CAS No.: 1394079-41-4
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DGN462, a potent DNA-alkylating agent, shows anti-tumor activity, such as acute myeloid leukemia (AML). DGN462 can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
Cat. No.: HY-W111005
CAS No.: 1086-00-6
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1-Chloromethylpyrene is an alkylating agent that enters the DNA double helix structure through intercalation, forms covalent bonds with electrophilic groups, resulting in DNA cross-linking, thereby inhibiting the proliferation of tumor cells .
Cat. No.: HY-16325
CAS No.: 250159-48-9
Synonyms: SM-11355 hydrate
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Miriplatin hydrate (SM-11355 hydrate) is a chemotherapy agent which belongs to the class of alkylating agents.
Cat. No.: HY-136327
CAS No.: 10477-72-2
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Phenylacetic acid mustard is the major metabolite of the cancer chemotherapeutic agent Chlorambucil (HY-13593). Chlorambucil is an alkylating agent with antitumor activity .
Cat. No.: HY-107770
CAS No.: 1613286-58-0
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Duocarmycin MB is an antibody agent conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MB can be used against multi-agent resistant cell lines.
Cat. No.: HY-18987
CAS No.: 1613286-57-9
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Duocarmycin MA is an antibody agent conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MA can be used against multi-agent resistant cell lines.
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Procarbazine is an orally active alkylating agent, with anticancer activity. Procarbazine can be used in Hodgkin's disease research .
Cat. No.: HY-13739
CAS No.: 58994-96-0
Synonyms: MCNU
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Ranimustine (MCNU) is a nitrosourea alkylating agent, can be used for research of chronic myelogenous leukemia and polycythemia vera .
Synonyms: (+)-Isoalantolactone (Standard); Isohelenin (Standard)
Cat. No.: HY-136289
CAS No.: 932744-62-2
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MB-VC-MGBA is a agent-linker conjugate for ADC with potent antitumor activity by using MGBA (minor-groove-binding DNA-alkylating agent), linked via the ADC linker MB-VC .
Thio-TEPA (Standard) is the analytical standard of Thio-TEPA. This product is intended for research and analytical applications. Thio-TEPA is a DNA alkylating agent, with antitumor activity.
Cat. No.: HY-148091
CAS No.: 1164275-01-7
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Duocarmycin analog-2 is a potent DNA alkylating agent. Duocarmycin analog-2 can be used of synthetic immunoconjugate. Duocarmycin analog-2 has antitumor activity .
Cat. No.: HY-131085
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Desmethyl Vc-seco-DUBA consists a cleavable ADC linker (Desmethyl Vc-seco) and a DNA alkylating agent (DUBA). Desmethyl Vc-seco-DUBA can be used in the synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-139453A
CAS No.: 2412580-47-1
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LP-284 is a potent DNA alkylating agent that kills solid tumours. LP-284 can be used in the studies of hematologic cancers with compromised DNA repair, such as mantle cell lymphoma (MCL) .
Cat. No.: HY-135901
CAS No.: 2412924-07-1
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Py-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Py-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
