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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
96 Results for "
cortisol
" in MedChemExpress (MCE) Product Catalog:
Products (96)
96 Results for "cortisol" in MCE Product Catalog:
Cat. No.: HY-P4413
CAS No.: 1815617-95-8
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Cat. No.: HY-N13191
CAS No.: 83036-64-0
Synonyms: Ingenol 3-benzoate
Target:
Cat. No.: HY-17461S
CAS No.: 2350278-95-2
Cat. No.: HY-141914S
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Hydrocortisone phosphate (Hydrocortisone 21-phosphate) is a derivative of the glucocorticoid Hydrocortisone hemisuccinate (HY-B1402) that increases serum luteinizing hormone (LH) levels. Hydrocortisone phosphate increases the activity of magnesium-dependent polymerases in the nucleolus. Hydrocortisone phosphate also serves as a substrate for alkaline phosphatase to localize phosphatases that hydrolyze steroid phosphates, and the role of alkaline phosphatase has been validated in adult mouse tissues .
Cat. No.: HY-77839S1
CAS No.: 1271728-08-5
Synonyms: 11-Deoxycortisol-d2; cortexolone-d2; Reichstein's substance S-d2
Cat. No.: HY-W684071
CAS No.: 1719-79-5
Synonyms: 20α-DHF
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Cat. No.: HY-19814
CAS No.: 91935-26-1
Synonyms: RU-40555
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Toripristone (RU-40555) is a cortisol receptor inhibitor. Toripristone combined with clarithromycin can increase the antibacterial activity of Mycobacterium avium complex infection .
Cat. No.: HY-P4493
CAS No.: 1926163-12-3
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Cat. No.: HY-W741872
CAS No.: 516-41-6
Synonyms: 5α-DHF
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Cat. No.: HY-17461AR
CAS No.: 50-04-4
Synonyms: Cortisone 21-acetate (Standard)
Cat. No.: HY-N8460AR
CAS No.: 1852-36-4
Synonyms: cortisol 21-sulfate sodium (Standard)
Category:
Cat. No.: HY-141728
CAS No.: 789440-10-4
Synonyms: BCIPP
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Cat. No.: HY-106605
CAS No.: 61325-80-2
Synonyms: LY 120363
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Flumezapine (LY 120363) is a potent and balanced antagonist of the dopamine D2 receptor and the 5-hydroxytryptamine receptor (5-HT receptor). Flumezapine does not alter the increase in serum cortisol caused by κ-opioid receptor agonists. Flumezapine inhibits the conditioned avoidance response in rats and has a low risk of extrapyramidal side effects. Flumezapine can be used in antipsychotic research .
Cat. No.: HY-W744549
CAS No.: 116-58-5
Synonyms: 20β-DHF
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Cat. No.: HY-151140
CAS No.: 3031098-46-8
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CYP11B1-IN-2 (compound 7aa) is an orally active, potent and selective CYP11B1 inhibitor, with IC50 values of 9 nM and 25 nM for human CYP11B1 and rat CYP11B1, respectively. CYP11B1-IN-2 can be used for the research of diseases caused by excessive cortisol .
Cat. No.: HY-101324
CAS No.: 64022-27-1
Synonyms: CPP
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MK-212 (CPP) is an orally active, blood-brain barrier permeable agonist of 5-HT1C, 5-HT2 and 5-HT1A receptors. MK-212 induces hyperthermia, nausea, arousal, irritability and restlessness, inhibits the elevation of plasma cortisol and prolactin, and reduces feelings of calmness and overall positive affect. MK-212 mediates anxiety-like behaviors and motor inhibition. MK-212 is applicable to research related to schizophrenia and anxiety disorders .
Cat. No.: HY-141944S
CAS No.: 2687961-03-9
Cat. No.: HY-12502B
CAS No.: 111011-53-1
Synonyms: NZ-105 hydrochloride; (±)-Efonidipine hydrochloride
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Research Areas:
Efonidipine (NZ-105) hydrochloride is an orally active dual L-type and T-type calcium channel blocker (CCB) with IC50 values of 1.8 and 350 nM, respectively. Efonidipine hydrochloride inhibits SARS-CoV-2 main protease. Efonidipine hydrochloride modulates adrenal steroidogenesis by increasing the expression of steroidogenic acute regulatory protein (StAR), dbcAMP-or angiotensin II-induced StAR mRNA expression and DHEA-S production, while suppressing the biosynthesis of aldosterone and cortisol. Efonidipine hydrochloride reduces plasma aldosterone levels in vivo. Efonidipine hydrochloride improves cardiac function in heart failure models by inhibiting T-type calcium channels (via both tonic and use-dependent blockade), independently of blood pressure reduction. Efonidipine hydrochloride can be used for research in hypertension, heart failure, and disorders involving dysregulated steroid hormone synthesis .
Cat. No.: HY-154758S
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
