Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
376 Results for "
CT
" in MedChemExpress (MCE) Product Catalog:
Products (376)
376 Results for "CT" in MCE Product Catalog:
Cat. No.: HY-153996
CAS No.: 2523435-18-7
CT1113 is a selective, orally active USP25/USP28 inhibitor. CT1113 inhibits cancer cell proliferation, induces apoptosis, and causes G2/S phase cell cycle arrest. CT1113 reduces the levels of total BCR-ABL1, phosphorylated BCR-ABL1, total STAT5, and phosphorylated STAT5, but does not alter the mRNA level of BCR-ABL1. CT1113 is applicable to research related to pancreatic cancer, colon cancer, and acute leukemia .
Cat. No.: HY-P99620
CAS No.: 1443004-15-6
Synonyms: CT-P22; CT120
Target:
Research Areas:
Cat. No.: HY-16433
CAS No.: 79714-31-1
Synonyms: CT 112
Target:
Research Areas:
Risarestat (CT-112), an aldose reductase inhibitor, is developed for the treatment of diabetic complications.
Target:
Research Areas:
CT-2584 is a chemotherapeutic compound that reduces the expression of NKEF-B in several tumor cell types and kills tumor cells by inducing the production of ROS in mitochondria, commonly used in cancer research .
Cat. No.: HY-P99346
CAS No.: 2444308-95-4
Synonyms: CT-P59
Research Areas:
Cat. No.: HY-175613
DOTA-ALB-02 is an albumin-bound FAP inhibitor (FAPI) ligand. DOTA-ALB-02 labeled with 177Lu has a high FAP-binding affinity and enhanced tumor uptake and retention with a significant tumor/nontarget ratio. DOTA-ALB-02 can be used for PET/CT and SPECT/CT imaging of cancers, especially late-stage cancers .
Cat. No.: HY-P990077
CAS No.: 1036730-42-3
Synonyms: CT-011; MDV9300
Target:
Research Areas:
Cat. No.: HY-P990842
Target:
Research Areas:
Synonyms: 5-CT
Target:
Research Areas:
5-Carboxamidotryptamine (5-CT) is a 5-HT1A, 5-HT1B, 5-HT1D, 5-HT5A, 5-HT7 receptor agonist . 5-Carboxamidotryptamine has a Ki value of 4.6 nM for cloned human 5-HT5A receptor. 5-Carboxamidotryptamine causes a dose-dependent reduction in rectal temperature of mice .
Cat. No.: HY-10182C
CAS No.: 2109414-84-6
Synonyms: CHIR-99021 dihydrochloride; CT99021 dihydrochloride
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Laduviglusib dihydrochloride (CHIR-99021 dihydrochloride; CT99021 dihydrochloride) is a potent, selective and orally active GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib dihydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib dihydrochloride is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib dihydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib dihydrochloride induces autophagy .
Cat. No.: HY-176772
CAS No.: 3106015-71-5
Research Areas:
QHL-1618 is a tumor microenvironment-activated drug conjugate. QHL-1618 inhibits the tumor growth in various tumor models, such as HT-1080 xenograft, CT-26 xenograft .
Cat. No.: HY-16449
CAS No.: 937273-04-6
Synonyms: CT-1578
Research Areas:
SB1578 (CT-1578) is a selective JAK2 and FLT3 inhibitor with an IC50 of 46 nM and 60 nM, respectively. SB1578 exhibits high selectivity for other kinase targets. SB1578 can be used for the study of non-oncology indication rheumatoid arthritis .
Cat. No.: HY-109084A
Synonyms: CT-707 tetrahydrochloride
Conteltinib tetrahydrochloride (CT-707 tetrahydrochloride) is the tetrahydrochloride salt form of Conteltinib (HY-109084). Conteltinib tetrahydrochloride is the inhibitor for FAK (IC50=1.6 nM), ALK, and Pyk2. Conteltinib tetrahydrochloride exhibits a synergistic anti-tumor efficacy with Cabozantinib (HY-13016) .
Cat. No.: HY-19704
CAS No.: 1233363-33-1
Synonyms: CT327; SNA-120
Target:
Research Areas:
Pegcantratinib (CT327) is a potent and selective TRKA antagonist with activity against TRKB and TRKC. Pegcantratinib can be used for research of CYLD cutaneous syndrome (CCS) and inflammatory dermatoses, such as psoriasis and concomitant pruritus .
Cat. No.: HY-P11237
CAS No.: 2869147-44-2
Synonyms: CT-388
Target:
Research Areas:
Enicepatide (CT-388) is a cAMP signal-biased dual GLP-1R and GIPR agonist peptide, with an EC50 value of 0.087 nM for GLP-1R cAMP, and an EC50 value of 2.47 nM for GIPR cAMP. Enicepatide activates the cAMP signaling pathway, while recruiting only minimal amounts of β-arrestin-2 at both targets and reducing receptor internalization levels. Enicepatide improves glycemic control, reduces body weight, suppresses appetite, and ameliorates the pathological conditions of metabolic dysfunction-associated steatohepatitis. Enicepatide can be used in the research of obesity, type 2 diabetes, and metabolic dysfunction-associated steatohepatitis .
Cat. No.: HY-172030
CAS No.: 61638-10-6
Target:
Research Areas:
2C-T hydrochloride is an analog of Mescaline and 2C-T-2 . Mescaline and 2C-T-2 have psychoactive effects.
Cat. No.: HY-175612
DOTA-ALB-01 is an albumin-bound FAP inhibitor (FAPI) ligand. DOTA-ALB-01 labeled with 68Ga or 177Lu has a high FAP-binding affinity and enhanced tumor uptake and retention. DOTA-ALB-01 can be used for PET/CT and SPECT/CT imaging of cancers, especially late-stage cancers .
Cat. No.: HY-P11318
CAS No.: 2170388-37-9
Target:
Research Areas:
Cat. No.: HY-P10652
CAS No.: 2094604-98-3
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
