719 Results for "

Enzyme Substrate

" in MedChemExpress (MCE) Product Catalog:
Products (719)

719 Results for "Enzyme Substrate" in MCE Product Catalog:

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1 Cited Publications
Cat. No.: HY-15906
CAS No.: 122341-56-4
Purity:  99.93%
Synonyms: Lumi-Phos Plus; Lumigen PPD; PPD
AMPPD (Lumi-Phos Plus; Lumigen PPD) is a chemiluminescent substrate for alkaline phosphatase (APase). AMPPD is hydrolyzed by APase to generate an unstable dioxetane intermediate, and the intermediate releases a chemiluminescent signal when it decomposes. The luminescent signal of AMPPD can be detected by highly sensitive equipment, thereby achieving quantitative analysis of the target molecule. AMPPD can be used in ultrasensitive enzyme-linked immunosorbent assays (such as quantitative detection of human tissue kininogen), chemiluminescent detection of proteins and nucleic acids, and other fields .
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1 Cited Publications
Cat. No.: HY-B1746
CAS No.: 529-96-4
Pyridoxamine 5′-phosphate is the active form of vitamin B6 bound to phosphoric acid. Pyridoxamine 5′-phosphate is the aminated form of Pyridoxal 5'-?phosphate monohydrate (HY-W011727A) and as co-factor of a variety of enzymes central metabolite, potent antioxidant, vitamin B6 vitamer and enzyme substrate. Pyridoxamine 5′-phosphate can be interconverted with pyridoxal 5'-phosphate hydrate .
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1 Cited Publications
Cat. No.: HY-P3008
CAS No.: 84195-52-8
Research Areas:  

Others

Submandibular mucin is a high molecular weight glycoprotein that is used as a substrate for the viral enzyme neuraminidase .
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1 Cited Publications
Cat. No.: HY-P4476
CAS No.: 72682-69-0
Target:  

Ser/Thr Protease

Research Areas:  

Others

Suc-AAPA-pNA is a substrate for chymotrypsin A and elastase. Suc-AAPA-pNA can be used for enzyme activity assay .
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1 Cited Publications
Cat. No.: HY-P1004A
CAS No.: 61970-00-1
Target:  

Fluorescent Dye

Research Areas:  

Others

Luciferase, firefly is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles. Luciferase, firefly catalytic substrate is D-luciferin (HY-12591B) .
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1 Cited Publications
Cat. No.: HY-B0150S
CAS No.: 347841-88-7
Synonyms: Niacinamide-d4; Nicotinic acid amide-d4
Nicotinamide-d4 is the deuterium labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.
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1 Cited Publications
Cat. No.: HY-P3722
CAS No.: 192723-42-5
Target:  

Fluorescent Dye MMP

Research Areas:  

Others

Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescent substrate peptide that can be used to detect ADAM9, ADAM10, and tumor necrosis factor-α converting enzyme (TACE/ADAM17). Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescence resonance energy transfer-based substrate, and its activity can be determined by changes in fluorescence intensity upon cleavage (Ex = 320 nm ; Em = 405 nm) .
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1 Cited Publications
Cat. No.: HY-P3722A
Target:  

Fluorescent Dye MMP

Research Areas:  

Others

Mca-PLAQAV-Dpa-RSSSR-NH2 TFA is a fluorescent substrate peptide that can be used to detect ADAM9, ADAM10, and tumor necrosis factor-α converting enzyme (TACE/ADAM17). Mca-PLAQAV-Dpa-RSSSR-NH2 TFA is a fluorescence resonance energy transfer-based substrate, and its activity can be determined by changes in fluorescence intensity upon cleavage (Ex = 320 nm ; Em = 405 nm) .
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1 Cited Publications
Cat. No.: HY-B0952
CAS No.: 123-82-0
Synonyms: Tuaminoheptane
Target:  

Adrenergic Receptor

Research Areas:  

Neurological Disease

2-Aminoheptane (Tuaminoheptane) is a norepinephrine transporter inhibitor. 2-Aminoheptane binds to norepinephrine transporter via ionic and hydrophobic interactions to block norepinephrine uptake. 2-Aminoheptane deactivates ω-TAmla enzyme, reduces recombinant whole cell stability, and acts as an amino group donor substrate for ω-TA and ω-TAmla enzymes. 2-Aminoheptane can be used in research on depression and Alzheimer's disease .
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1 Cited Publications
Cat. No.: HY-15927
CAS No.: 2492-87-7
4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate for β-glucosidase. 4-Nitrophenyl β-D-glucopyranoside is converted to a colored product, p-nitrophenol that is easily detected spectrophotometrically at 405 nm when used in a β-glycosidase assay. 4-Nitrophenyl β-D-glucopyranoside is hydrolysed through intramolecular nucleophilic catalysis by the phosphate group in the 2-position. 4-Nitrophenyl β-D-glucopyranoside is promising for research of postmenopausal osteoporosis .
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1 Cited Publications
Cat. No.: HY-E70157
Synonyms: EC:2.4.1.68; FUT8; α1-6FucT
Fucosyltransferase 8 (EC:2.4.1.68; FUT8; α1-6FucT) is a glycosyl transferase and catalyzes the transfer of a fucose residue from GDP-fucose to the innermost N-acetylglucosamine residue of N-glycans .
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1 Cited Publications
Cat. No.: HY-P2802
CAS No.: 9001-42-7
Synonyms: α-D-Glucosidase, Yeast
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-Glucosidase, Yeast (α-D-Glucosidase, Yeast), a carbohydrate hydrolyzing enzyme, catalyzes the liberation of α-glucose from the non-reducing end of the substrate. α-Glucosidase can facilitate the absorption of glucose by the small intestine. Inhibition of α-Glucosidase is an effective management of non-insulin-dependent diabetes mellitus (NIDDM) .
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1 Cited Publications
Cat. No.: HY-16955A
CAS No.: 1380078-95-4
Synonyms: ACHN 490 sulfate
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Plazomicin (ACHN 490) sulfate is a semi-synthetic aminoglycoside Antibiotic. Plazomicin sulfate acts as a substrate for Aminoglycoside acetyltransferase and Aminoglycoside phosphotransferase. Plazomicin sulfaten is not modified by various common aminoglycoside-modifying enzymes. Plazomicin sulfate selectively inhibits MATE2-K. Plazomicin sulfate exhibits activity against multidrug-resistant bacteria, including carbapenem-resistant Enterobacterales .
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1 Cited Publications
Cat. No.: HY-20897A
CAS No.: 25197-99-3
5-Bromo-L-tryptophan is a substrate of PLP-dependent enzyme AetE, as well as an indole alkaloid and Amino acid derivative. 5-Bromo-L-tryptophan can be isolated from Semenospongia sp. 5-Bromo-L-tryptophan can be converted into 5-bromoindole (HY-30236) via AetE-mediated catalysis. 5-Bromo-L-tryptophan is applicable to colon cancer research .
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1 Cited Publications
Cat. No.: HY-W145649
CAS No.: 15673-79-7
Research Areas:  

Others

Ribose-5-phosphate Barium Salt is an organic compound that belongs to the monosaccharide phosphate family. It is commonly used as an intermediate in various biochemical pathways, especially in the biosynthesis of nucleotides and coenzymes. Ribose-5-phosphate Barium Salt has several applications in biochemical research, including as a precursor for the synthesis of other phosphorylated sugars and as a substrate for enzymes involved in the pentose phosphate pathway. In addition, it can be used as an energy source and dietary supplement for certain microorganisms.
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1 Cited Publications
Cat. No.: HY-B2228
CAS No.: 9001-92-7
Proteinase, Aspergillus oryzae is a serine protease that hydrolyzes peptide bonds in protein substrates, preferring alkaline conditions (optimal pH 10.5). It efficiently degrades casein, poly-L-glutamic acid, and poly-L-lysine, with activity irreversibly inhibited by diisopropylfluorophosphate (DFP) and potato inhibitor. This enzyme catalyzes proteolysis via serine residues in its active site, finding applications in food processing (e.g., soy sauce fermentation), detergents, and leather industries due to its high yield in solid-state fermentation and cost-effective production.
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1 Cited Publications
Cat. No.: HY-E70005H
CAS No.: 9001-12-1
Target:  

Proteasome

Research Areas:  

Cardiovascular Disease

Collagenase, Type VIII is a mixed enzyme derived from Clostridium histolyticum that contains collagenase, a nonspecific protease, and a clostripain. Collagenase, Type VIII can hydrolyze Type VIII collagen and may be used to study the formation of atherosclerosis. Type VIII collagen is a regulator of endothelial cell differentiation and angiogenesis, a substrate for cell adhesion and migration such as smooth muscle cells, and may accumulate in atherosclerosis. After endotoxin activates the expression of Collagenase, Type VIII, it can reduce the production of Type VIII collagen and has the potential to inhibit atherosclerosis .
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1 Cited Publications
Cat. No.: HY-145934A
CAS No.: 1611490-64-2
Purity:  99.74%
UDP-GlcNAz disodium is the analogue of UDP-GlcNAc disodium (HY-112174). UDP-GlcNAc disodium is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GlcNAc from the nucleotide sugar to a saccharide or peptide acceptor. UDP-GlcNAc disodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
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1 Cited Publications
Cat. No.: HY-48999A
CAS No.: 3033987-42-4
Target:  

EGFR

Research Areas:  

Cancer

FSK hydrochloride is fluorosulfonyloxybenzoyl-L-lysine, which features a long, flexible aryl fluorosulfate-containing side chain that can reach protein sites inaccessible to covalent conjugation. FSK hydrochloride modifies nanomolecules to target epidermal growth factor receptor (EGFR), resulting in irreversibly bound covalent interactions. Through genetically encoded chemical crosslinking, FSK hydrochloride captures unknown enzyme-substrate interactions in living cells, targets residues other than Cys, and mediates crosslinking at the binding periphery. FSK hydrochloride enables the construction of a bioreactive SuFEx system for generating covalent bonds in various proteins both in vitro and in vivo .
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1 Cited Publications
Cat. No.: HY-145934
CAS No.: 653600-61-4
Purity:  99.78%
Synonyms: UDP-N-azidoacetylgalactosamine disodium
UDP-GalNAz (UDP-N-azidoacetylgalactosamine) disodium is the analogue of UDP-GalNAc disodium (HY-114365). UDP-GalNAc disodium is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor. UDP-GalNAz disodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
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