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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
638 Results for "
MDA PCa 2b
" in MedChemExpress (MCE) Product Catalog:
Products (638)
638 Results for "MDA PCa 2b" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P7212
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL19; IL-19; Interleukin 19; MDA1; ZMDA1; Melanoma Differentiation Associated Protein-Like Protein; NG.1; Interleukin-19; IL-10C; Melanoma Differentiation-Associated Protein-Like Protein
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P7213
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL19; IL-19; Interleukin 19; MDA1; ZMDA1; Melanoma Differentiation Associated Protein-Like Protein; NG.1; Interleukin-19; IL-10C; Melanoma Differentiation-Associated Protein-Like Protein
Species:
Mouse
Source:
E. coli
2
2 Cited Publications
Synonyms: 10-Acetylphenoxazine
HJ-PI01 (10-Acetylphenoxazine) is an orally active Pim-2 inhibitor. HJ-PI01 induces apoptosis and autophagic cell death of cancer cells. HJ-PI01 inhibits tumor growth in MDA-MB-231 xenograft mice. HJ-PI01 can be used for cancer research .
2
2 Cited Publications
Target:
Research Areas:
CAIX Inhibitor S4 is a potent and selective inhibitor of carbonic anhydrase IX/XII (CA IX/XII), with a Ki of 7 nM and 2 nM, respectively. CAIX Inhibitor S4 also inhibits CA II and CA I (Ki=546 and 5600 nM, respectively). CAIX Inhibitor S4 can inhibit the number of lung metastasis in orthotopic MDA-MB-231 mouse model without affecting primary tumor growth .
2
2 Cited Publications
Target:
Research Areas:
SP-96 is a highly potent, selective and non-ATP-competitive Aurora B (IC50=0.316 nM) inhibitor and shows >2000 fold selectivity against FLT3 and KIT. SP-96 shows selective growth inhibition in NCI60 screening, incluing MDA-MD-468 (GI50=107 nM). SP-96 can be used for the research of triple negative breast cancer (TNBC) .
2
2
2 Cited Publications
Research Areas:
EF24, a curcumin analogue, is an NF-kB inhibitor with great anti-tumor efficacy and oral bioavailability via deactivation of the MAPK/ERK signaling pathway in oral squamous cell carcinoma (OSCC). EF24 is active against melanoma and breast cancer cell lines with GI50 values of 0.7 μM and 0.8 μM, respectively. EF24 induces cell cycle arrest and apoptosis in MDA-MB-231 human breast cancer cells and DU-145 human prostate cancer cells. EF24 increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK .
2
2
2 Cited Publications
Synonyms: Ordenina hydrochloride; Peyocactine hydrochloride
1
Narmafotinib (AMP-945) is an orally active inhibitor of the enzyme focal adhesion kinase (FAK, KD=0.21 nM). Narmafotinib inhibits autophosphorylation of 397Y-FAK in MDA-MB-231 cells with an IC50=7 nM and exhibits low general cellular toxicity (IC50=2.7 μM, MDA-MB-231 cells). Narmafotinib can be used for anti-cancer study .
1
1 Cited Publications
Cat. No.: HY-P0021A
CAS No.: 108963-70-8
Synonyms: Spectrozyme PCa; Chromozym PCa diacetate
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-N12127
CAS No.: 899430-01-4
Target:
1
1 Cited Publications
Cat. No.: HY-P700200AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL24; IL-4-Induced Secreted Protein; Prev. ST16; Mob-5; Interleukin-24; MDA7; IL10B; Melanoma Differentiation Association Protein 7; IL-24; Suppression Of Tumorigenicity 16 Protein; C49A; Melanocyte-Associated MDA-7; FISP; MDA-7; Suppression Of Tumorigeni
Species:
Mouse
Source:
E. coli
1
1
1
1
1 Cited Publications
Cat. No.: HY-162143
CAS No.: 727686-80-8
SKI-349 is a dual-targeted inhibitor of sphingosine kinase 1/2 (SPHK1/2) and microtubule assembly (MDA). SKI-349 has anticancer activity. SKI-349 can inhibit the vitality, invasion, and AKT/mTOR signaling pathway of liver cells .
1
1 Cited Publications
Synonyms: N-Lauroyl-D-erythro-sphingosine; N-Laurylsphingosine
Target:
Research Areas:
C12-Ceramide (N-Lauroyl-D-erythro-sphingosine), a naturally occurring ceramide, is formed by hydrolysis of C12 sphingomyelin. C12-Ceramide can enhance the Doxorubicin toxicity in MDA-MB-231 cells. C12-Ceramide also can be used to diagnose types A and B Niemann-Pick disease .
1
1 Cited Publications
Target:
Research Areas:
EUK-134, a synthetic superoxide dismutase and catalase mimetic, protects rat kidneys from ischemia-reperfusion-induced damage. EUK-134 is a superoxide dismutase (SOD) mimetics (SODm) with catalase activity. EUK-134 is a mitoprotective antioxidant. EUK-134 reduces the expression of NF-κB, MDA level, and protein carbonylation in H9C2 cells .
1
Category:
Cardiovascular Disease Monophenols Ketones, Aldehydes, Acids Phenols Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
