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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
201 Results for "
alpha-synuclein
" in MedChemExpress (MCE) Product Catalog:
Products (201)
201 Results for "alpha-synuclein" in MCE Product Catalog:
Cat. No.: HY-P3140A
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Cat. No.: HY-P4704A
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α-Synuclein inhibitor 10 (compound a8) inhibits the activity of α-Syn aggregation with low IC50 value (1.08 μM). α-Synuclein inhibitor 10 exhibits good binding affinity to α-Syn residues. α-Synuclein inhibitor 10 can be used in the research of Parkinson's disease (PD) .
Cat. No.: HY-135902
CAS No.: 502139-01-7
Synonyms: NSC 377363
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Synucleozid (NSC 377363) is a potent inhibitor of the SNCA mRNA that encodes α-synuclein protein. Synucleozid selectively targets the α-synuclein mRNA 5′ UTR at the designed IRE site, decreases the amount of SNCA mRNA loaded into polysomes and thereby inhibits SNCA translation. Synucleozid has the potential for the investigation of Parkinson’s disease .
Cat. No.: HY-P3140
CAS No.: 440645-08-9
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Cat. No.: HY-178920
CAS No.: 676458-63-2
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α-Synuclein-IN-17 (Compound 10) is an α-Synuclein inhibitor, with an IC50 value of 9 μM. α-Synuclein-IN-17 exhibits potent inhibitory activity against both in-vitro assembled asyn fibrils and LBD brain tissue-amplified asyn fibrils. α-Synuclein-IN-17 can be used for the study of Parkinson's disease (PD) and Lewy Body Disease (LBD) .
Cat. No.: HY-163145
CAS No.: 3095291-54-3
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α-Synuclein inhibitor 11 (compound 1) is a selective α-synuclein (α-syn) oligomer formation inhibitor. α-Synuclein inhibitor 11 does not inhibits tau 4R (isoforms 0N4R, 2N4R) or p-tau (isoform 1N4R). α-Synuclein inhibitor 11 can be used for Parkinson's disease (PD) research .
Cat. No.: HY-176925
CAS No.: 3056154-68-5
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α-Synuclein aggregate binder 2 (Compound 1) is a specific alpha-synuclein binder with a Ki of 1.6 nM. α-Synuclein aggregate binder 2 has a weak binding affinity for β-amyloid aggregates with a Ki of 295 nM. α-Synuclein aggregate binder 2 can be used as a tracer in Parkinson's disease .
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Sulfamerazine (RP2632) sodium is a brain-penetrant and orally active sulfonamide antibiotic and α-synuclein inhibitor with human α-synuclein KD of 352 μM. Sulfamerazine sodium inhibits the synthesis of dihydrofolate by bacteria, thereby inhibiting bacterial growth. Sulfamerazine sodium inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine sodium can be used for the research of Parkinson’s disease and bacterial infection .
Cat. No.: HY-P10360
CAS No.: 2816095-52-8
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Cat. No.: HY-177647
CAS No.: 2411937-33-0
Synonyms: BIIB-101; ION-464
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Movronersen is an antisense oligonucleotide targeted to α-synuclein.
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ELN484228 is a blocker of α-synuclein which is a key protein in Parkinson’s disease.
Cat. No.: HY-175737
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α-synuclein-IN-16 (Compound H1) is a α-synuclein inhibitor. α-synuclein-IN-16 significantly inhibits the secondary nucleation in α-synuclein aggregation. α-synuclein-IN-16 can be used for Parkinson’s disease research .
Cat. No.: HY-P5043
CAS No.: 2243206-99-5
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Cat. No.: HY-N15613
CAS No.: 408324-13-0
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Cat. No.: HY-P4704
CAS No.: 154040-19-4
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Cat. No.: HY-175308
CAS No.: 414880-30-1
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α-Synuclein inhibitor 15 (Compound 1) is an inhibitor targeting the fibrillation growth of α-synuclein (IC50=18 μM). α-Synuclein inhibitor 15 is promising for research of neurodegenerative diseases, such as Parkinson's disease (PD) and Lewy body dementia (LBD) .
Cat. No.: HY-N10306
CAS No.: 3034046-94-8
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Cat. No.: HY-177647A
Synonyms: BIIB-101 sodium; ION-464 sodium
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Movronersen sodium is an antisense oligonucleotide targeted to α-synuclein.
Cat. No.: HY-P5041
CAS No.: 2170181-52-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
