Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
75 Results for "
antitubercular agent
" in MedChemExpress (MCE) Product Catalog:
Products (75)
75 Results for "antitubercular agent" in MCE Product Catalog:
Cat. No.: HY-W716669
CAS No.: 952-54-5
Target:
Research Areas:
Morinamide is an antibacterial agent, antitubercular agent and Pyrazine (HY-W013040) derivative. Morinamide can be used in the research of tuberculosis .
Benzothiohydrazide is an analogue of anti–tubercular agent Isoniazid. Benzothiohydrazide exhibits anti–tubercular activity, with MICs of 132 μM and 264 μM for M. tuberculosis wild type (H37Rv) and clinical mutant strains (IC1 and IC2) .
Antitubercular agent-33 is a 2-aminothiazole derivative, shows potent antintubercular activity against Mycobacterium tuberculosis (Mtb) .
Cat. No.: HY-152138
CAS No.: 2874263-74-6
Antituberculosis agent-8 (Compound 9i) is an antitubercular agent with an MIC of 3.53 μM (1.6 μg/mL) against M. tuberculosis H37Rv. Antituberculosis agent-8 also shows good antifungal activity against A. niger with an MIC of 62.50 μM .
Cat. No.: HY-168123
CAS No.: 2956713-87-2
Antitubercular agent-47 (compund 5C) shows potent activity against tuberculosis and was effective against DS/MDR/XDR clinical isolates .
Cat. No.: HY-W002297
CAS No.: 21568-87-6
Target:
Research Areas:
(S)-3-Aminoazepan-2-one is the structural unit of the antitubercular peptide, serving as the core scaffold of a hexapeptide antibacterial agent. (S)-3-Aminoazepan-2-one is promising for research of tuberculosis .
Cat. No.: HY-150554
Antitubercular agent-29 (compound 6xa) is a potent agent resistant (DR) Mycobacterium tuberculosis (Mtb) inhibitor with MIC of 0.03 μg/mL against agent-susceptible (DS)-Mtb strains, MIC of 0.03-0.06 μg/mL against DR-Mtb strains, and favourable selectivity (SI>40) against Vero cells .
Cat. No.: HY-183998
CAS No.: 1356814-93-1
Antitubercular agent-60 is an orally active antitubercular agent. Antitubercular agent-60 targets the arabinogalactan biosynthesis pathway in Mycobacterium tuberculosis. Antitubercular agent-60 can be used for the research of tuberculosis .
Cat. No.: HY-179673
Antitubercular agent-54 is an antitubercular agent with potent intramacrophage activity (EC50 = 0.68 μM). Antitubercular agent-54 shows a MIC of 0.31 μM against Mycobacterium tuberculosis (Mtb) H37Rv in cholesterol-containing medium. Antitubercular agent-54 can be used for the research of tuberculosis .
Cat. No.: HY-181008
Target:
Research Areas:
Antitubercular agent-56, a Questiomycin A (HY-N8439) derivative, is a potent and orally active antitubercular agent. Antitubercular agent-56 disrupts mycobacterial envelope integrity by inhibiting FabD (Kd = 9.39 μM; IC50 = 49.60 μM). Antitubercular agent-56 exhibits good intracellular antimycobacterial activity against Mycobacterium tuberculosis (MTB) and drug-resistant MTB both in vitro and in vivo. Antitubercular agent-56 can be used for research on tuberculosis (TB) .
Cat. No.: HY-124195
CAS No.: 461431-74-3
Antitubercular agent-57 is a selective antimycobacterial agent with low in vitro toxicity against mammalian cell lines including hepatocyte cell lines. Antitubercular agent-57 exhibits activity against drug-sensitive, multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis strains, and shows no cross-resistance with first-line or second-line antitubercular agents. Antitubercular agent-57 has no activity against Gram-positive bacteria, Gram-negative bacteria and fungal strains. Antitubercular agent-57 can be used in the research of tuberculosis and multidrug-resistant tuberculosis .
Cat. No.: HY-183551
Antitubercular agent-59 is an orally active antitubercular agent with an IC50 of 51 nM against Mycobacterium tuberculosis H37Rv. Antitubercular agent-59 inhibits growth of Bedaquiline (HY-14881)-resistant Rv0678G12C mutant strains. Antitubercular agent-59 exerts bactericidal activity in chronic tuberculosis mouse models with 1-Aminobenzotriazole (HY-103389) coadministration .
Cat. No.: HY-180854
Antitubercular agent-55 (Compound 2e) is an anti-tuberculous agent. Antitubercular agent-55 exhibits significant inhibitory activity against the standard strain of Mycobacterium tuberculosis H37Rv and also has moderate inhibitory activity against multidrug-resistant TB (MDR-TB). Antitubercular agent-55 has a strong affinity for the key enzyme InhA involved in the biosynthesis of mycotic acids. Antitubercular agent-55 can be used for research on tuberculosis infection caused by Mycobacterium tuberculosis.
Cat. No.: HY-149064
CAS No.: 2998587-72-5
Antituberculosis agent-9 (Compound 5a) is an orally active antitubercular agent with an MIC of 0.5 μg/mL against H37Ra .
Cat. No.: HY-N10992
CAS No.: 15914-62-2
Target:
Cat. No.: HY-146374
CAS No.: 2413006-62-7
Antibacterial agent 96 (compound 4k) is a potent antibacterial agent. Antibacterial agent 96 shows antitubercular activity against agent-susceptible and multidrug-resistantMycobacterium tuberculosis (M. tuberculosis) strains. Antibacterial agent 96 shows toxicity to HepG2 and Vero cells .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
